Results 71 to 80 of about 123,558 (314)

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz   +9 more
wiley   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Multi-stage sliding mode control design with optimal state estimator for load frequency regulation in hybrid-source power systems

open access: yesScientific Reports
The rapid growth of renewable energy sources (RES) and the increasing complexity of modern power systems (PSs) have introduced significant challenges for automatic load frequency control (LFC), including large uncertainties, disturbances, and reduced ...
Anh-Tuan Tran   +4 more
doaj   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan   +14 more
wiley   +1 more source

The Co-existence of Different Synchronization Types in Fractional-order Discrete-time Chaotic Systems with Non–identical Dimensions and Orders

open access: yesEntropy, 2018
This paper is concerned with the co-existence of different synchronization types for fractional-order discrete-time chaotic systems with different dimensions.
Samir Bendoukha   +6 more
doaj   +1 more source

Evolutionary Algorithms for Quantum Computers [PDF]

open access: yesAlgorithmica, 2013
Algorithmica, 68 (1)
Daniel Johannsen   +2 more
openaire   +3 more sources

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

Antenna performance optimisation using evolutionary algorithms [PDF]

open access: yes, 2010
This thesis investigates the novel idea of using evolutionary algorithms to optimise control and design aspects of active array antenna systems. Active arrays differ from most mechanically scanned antennas in that they offer the ability to control the ...
Ansell, D. W.
core  

Automatic Design of Decision-Tree Algorithms with Evolutionary Algorithms [PDF]

open access: yes, 2013
This study reports the empirical analysis of a hyper-heuristic evolutionary algorithm that is capable of automatically designing top-down decision-tree induction algorithms.
Alex Freitas   +9 more
core   +1 more source

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