Results 11 to 20 of about 46,371 (25)

The use of information theory in evolutionary biology [PDF]

Annals NY Acad. Sciences 1256 (2012) 49-65, 2011
Information is a key concept in evolutionary biology. Information is stored in biological organism's genomes, and used to generate the organism as well as to maintain and control it. Information is also "that which evolves". When a population adapts to a local environment, information about this environment is fixed in a representative genome. However,
arxiv   +1 more source

Cancer systems biology in the genome sequencing era: Part 2, evolutionary dynamics of tumor clonal networks and drug resistance [PDF]

, 2014
A tumor often consists of multiple cell subpopulations (clones). Current chemo-treatments often target one clone of a tumor. Although the drug kills that clone, other clones overtake it and the tumor reoccurs. Genome sequencing and computational analysis allows to computational dissection of clones from tumors, while singe-cell genome sequencing ...
arxiv   +1 more source

Evolution of macromolecular structure: a 'double tale' of biological accretion [PDF]

Science Progress 101(4):360-383, 2018, 2018
The evolution of structure in biology is driven by accretion and change. Accretion brings together disparate parts to form bigger wholes. Change provides opportunities for growth and innovation. Here we review patterns and processes that are responsible for a 'double tale' of evolutionary accretion at various levels of complexity, from proteins and ...
arxiv   +1 more source

Neutrality: A Necessity for Self-Adaptation [PDF]

Proceedings of the Congress on Evolutionary Computation (CEC 2002), 1354-1359., 2002
Self-adaptation is used in all main paradigms of evolutionary computation to increase efficiency. We claim that the basis of self-adaptation is the use of neutrality. In the absence of external control neutrality allows a variation of the search distribution without the risk of fitness loss.
arxiv  

GC3 Biology in Eukaryotes and Prokaryotes [PDF]

DNA Methylation - From Genomics to Technology, 2012, pp 55-68, 2012
We describe the distribution of Guanine and Cytosine (GC) content in the third codon position (GC3) distributions in different species, analyze evolutionary trends and discuss differences between genes and organisms with distinct GC3 levels. We scrutinize previously published theoretical frameworks and construct a unified view of GC3 biology in ...
arxiv  

Heuristic algorithms in Evolutionary Computations and modular organization of biological macromolecules: applications to directed evolution [PDF]

arXiv, 2019
A while ago, the ideas of evolutionary biology inspired computer scientists to develop a thriving nowadays field of evolutionary computation (EC), in general, and genetic algorithms (GA), in particular. At the same time, the directed evolution of biological molecules (in vitro evolution) is reasonably interpreted as an implementation of GA in ...
arxiv  

The contribution of statistical physics to evolutionary biology [PDF]

, 2011
Evolutionary biology shares many concepts with statistical physics: both deal with populations, whether of molecules or organisms, and both seek to simplify evolution in very many dimensions. Often, methodologies have undergone parallel and independent development, as with stochastic methods in population genetics.
arxiv   +1 more source

Biology-Derived Algorithms in Engineering Optimization [PDF]

Yang X.-S., Biology-derived algorithms in engineering optimization (chapter 32), in: Handbook of Bioinspired Algorithms and Applications (Eds. S. Olarius and A. Y. Zomaya), Chapman & Hall/CRC Press, pp. 589-600 (2005), 2010
Biology-derived algorithms are an important part of computational sciences, which are essential to many scientific disciplines and engineering applications. Many computational methods are derived from or based on the analogy to natural evolution and biological activities, and these biologically inspired computations include genetic algorithms, neural ...
arxiv  

Tangled Nature: a model of evolutionary ecology [PDF]

arXiv, 2001
We discuss a simple model of co-evolution. In order to emphasise the effect of interaction between individuals the entire population is subjected to the same physical environment. Species are emergent structures and extinction, origination and diversity are entirely a consequence of co-evolutionary interaction between individuals.
arxiv  

The evolutionary advantage of diploid sex [PDF]

arXiv, 2002
We modify the Penna Model for biological aging, which is based on the mutation-accumulation theory, in order to verify if there would be any evolutionary advantage of triploid over diploid organisms. We show that this is not the case, and that usual sex is always better than that involving three individuals.
arxiv