Results 71 to 80 of about 935,716 (329)
Underlying Principles of Natural Selection in Network Evolution: Systems Biology Approach
Evolutionary Bioinformatics, 2007 Systems biology is a rapidly expanding field that integrates diverse areas of science such as physics, engineering, computer science, mathematics, and biology toward the goal of elucidating the underlying principles of hierarchical metabolic and ...
Bor-Sen Chen, Wei-Sheng Wu
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iScience, 2023 Summary: Endosymbiosis with chemosynthetic Gammaproteobacteria is widely recognized as an adaptive mechanism of siboglinid tubeworms, yet evolution of these endosymbionts and their driving forces remain elusive.
Zhao-Ming Gao +7 more
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Evolutionary foundations for cancer biology [PDF]
Evolutionary Applications, 2013 AbstractNew applications of evolutionary biology are transforming our understanding of cancer. The articles in this special issue provide many specific examples, such as microorganisms inducing cancers, the significance of within‐tumor heterogeneity, and the possibility that lower dose chemotherapy may sometimes promote longer survival.
C. Athena Aktipis +2 more
openaire +3 more sources
FEBS Letters, EarlyView.Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez +3 more
wiley +1 more source
iScience, 2023 Summary: Placental mammals' ancestors were insectivores, suggesting that modern mammals may have inherited the ability to digest insects. Acidic chitinase (Chia) is a crucial enzyme hydrolyzing significant component of insects' exoskeleton in many ...
Eri Tabata +5 more
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Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Protocol for an agent-based model of recombination in bacteria playing a public goods game
STAR Protocols, 2023 Summary: Agent-based models are composed of individual agents coded for traits, such as cooperation and cheating, that interact in a virtual world based on defined rules.
Isaiah Paolo A. Lee +3 more
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A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Robust 3D modeling reveals spatiosyntenic properties of animal genomes
iScience, 2023 Summary: Animal genomes are organized into chromosomes that are remarkably conserved in their gene content, forming distinct evolutionary units (synteny).
Tereza Clarence +5 more
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Evolutionary biology and genetic techniques for insect control [PDF]
, 2015 The requirement to develop new techniques for insect control that minimize negative environmental impacts has never been more pressing. Here we discuss population suppression and population replacement technologies. These include sterile insect technique,
Bolton, Michael +2 more
core +1 more source