Results 101 to 110 of about 3,031,483 (337)
Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
Conservative and non-conservative evolutionary computations in connection with Wolf-Rayet binaries. [PDF]
D. Vanbeveren+3 more
openalex +1 more source
Editorial: Evolutionary computation-based machine learning and its applications for multi-robot systems. [PDF]
Ma L.
europepmc +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Exploring spatial programming through modularity based evolutionary computation
The application of evolutionary computing in architecture has advanced beyond active feedback to designers by integrating natural processes with computation to synchronize input from the final solution.
Resza Riskiyanto+2 more
doaj +1 more source
Evolutionary Computation Techniques for Nonlinear Programming Problems [PDF]
Zbigniew Michalewicz
openalex +1 more source
Egret Swarm Optimization Algorithm: An Evolutionary Computation Approach for Model Free Optimization. [PDF]
Chen Z+8 more
europepmc +1 more source
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner+6 more
wiley +1 more source
Particle swarm inspired optimization algorithm without velocity equation
This paper introduces Particle Swarm Without Velocity equation optimization algorithm (PSWV) that significantly reduces the number of iterations required to reach good solutions for optimization problems.
Mahmoud Mostafa El-Sherbiny
doaj +1 more source