Results 111 to 120 of about 250,700 (315)

Evolutionary Computation Techniques for Nonlinear Programming Problems [PDF]

, 1994
Zbigniew Michalewicz
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Exploring spatial programming through modularity based evolutionary computation

Journal of Architecture and Urbanism
The application of evolutionary computing in architecture has advanced beyond active feedback to designers by integrating natural processes with computation to synchronize input from the final solution.
Resza Riskiyanto, Ahmad Bayu Wibisono, Arnis Rochma Harani   +2 more
doaj   +1 more source

Egret Swarm Optimization Algorithm: An Evolutionary Computation Approach for Model Free Optimization. [PDF]

Biomimetics (Basel), 2022
Chen Z, Francis A, Li S, Liao B, Xiao D, Ha TT, Li J, Ding L, Cao X.   +8 more
europepmc   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

Creative AI Through Evolutionary Computation: Principles and Examples. [PDF]

SN Comput Sci, 2021
Miikkulainen R.
europepmc   +1 more source

Constructing a Tree from Homeomorphic Subtrees, with Applications to Computational Evolutionary Biology [PDF]

, 1999
Monika Henzinger, Valerie King, Tandy Warnow   +2 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Particle swarm inspired optimization algorithm without velocity equation

Egyptian Informatics Journal, 2011
This paper introduces Particle Swarm Without Velocity equation optimization algorithm (PSWV) that significantly reduces the number of iterations required to reach good solutions for optimization problems.
Mahmoud Mostafa El-Sherbiny
doaj   +1 more source

Heuristic algorithms in evolutionary computation and modular organization of biological macromolecules: Applications to in vitro evolution. [PDF]

PLoS One, 2022
Spirov AV, Myasnikova EM.
europepmc   +1 more source