Results 51 to 60 of about 46,925 (311)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Experimental dataset of charge and discharge patterns in a 1200Ah OpzS battery bankZenodo

Data in Brief
This dataset was generated from experiments on a bank of six 1200 Ah OPzS stationary batteries connected in series to form a 12 V storage system. Each cell was monitored for voltage, temperature, and electrolyte density using a DataTaker DT85M recorder ...
Javier Rocha, Ricardo Aguasca, Máximo Méndez   +2 more
doaj   +1 more source

Optimizing Team Sport Training With Multi-Objective Evolutionary Computation

International Journal of Computer Science in Sport, 2021
This research introduces a new novel method for mathematically optimizing team sport training models to enhance two measures of athletic performance using an evolutionary computation based approach.
Connor Mark, Faganan David, Watters Barry, McCaffery Fergal, O’Neill Michael   +4 more
doaj   +1 more source

Artificial selection methods from evolutionary computing show promise for directed evolution of microbes

eLife, 2022
Directed microbial evolution harnesses evolutionary processes in the laboratory to construct microorganisms with enhanced or novel functional traits. Attempting to direct evolutionary processes for applied goals is fundamental to evolutionary computation,
Alexander Lalejini, Emily Dolson, Anya E Vostinar, Luis Zaman   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

An overview of evolutionary computation [PDF]

, 1993
Evolutionary computation uses computational models of evolutionary processes as key elements in the design and implementation of computerbased problem solving systems. In this paper we provide an overview of evolutionary computation, and describe several evolutionary algorithms that are currently of interest.
William M. Spears, Kenneth A. De Jong, Thomas Bäck, David B. Fogel, Hugo de Garis   +4 more
openaire   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Evolutionary Computation for Air Transportation: A Survey

Mathematics
As the demand for air transportation continues to grow, airspace congestion, flight delays, operational costs, and safety have become important and challenging issues.
Rui Huang, Zong-Gan Chen
doaj   +1 more source

Design Exploration of Initial Bubbles for Higher-Speed Laser-Induced Microjets

IEEE Access, 2023
Laser-induced microjets are advantageous for yielding high-speed and convergent microjets shape. However, owing to the need for high-power laser devices, reducing the required laser power is a prerequisite for convenience in practical use.
Tatsumasa Ishikawa, Hiroyuki Nishida, Yoshiyuki Tagawa   +2 more
doaj   +1 more source