Results 61 to 70 of about 46,925 (311)

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Evolutionary Computation Applied To Algorithmic Composition

open access: yes, 2015
This paper presents an end-user interface that allows real time parametric control of sound events. It is an interactive environment in which evolutionary computation is applied to algorithmic composition.
Von Zuben F.   +3 more
core   +1 more source

ECF: A C++ framework for evolutionary computation

open access: yesSoftwareX
Metaheuristics have been shown to be efficient techniques for addressing a wide range of complex optimization problems. Developing flexible, reliable, and efficient frameworks for evolutionary computation metaheuristics is of great importance.
Domagoj Jakobovic   +3 more
doaj   +1 more source

Quality Diversity: A New Frontier for Evolutionary Computation

open access: yesFrontiers in Robotics and AI, 2016
While evolutionary computation and evolutionary robotics take inspiration from nature, they have long focused mainly on problems of performance optimization.
Justin K Pugh   +2 more
doaj   +1 more source

OEbBOA: A Novel Improved Binary Butterfly Optimization Approaches With Various Strategies for Feature Selection

open access: yesIEEE Access, 2020
Binary butterfly optimization approach (bBOA) is a recent high performing feature selection algorithm presented in 2018 which is based on the food foraging behavior of butterflies.
Bo Zhang   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

A Review of Gait Optimization Based on Evolutionary Computation

open access: yesApplied Computational Intelligence and Soft Computing, 2010
Gait generation is very important as it directly affects the quality of locomotion of legged robots. As this is an optimization problem with constraints, it readily lends itself to Evolutionary Computation methods and solutions.
Daoxiong Gong, Jie Yan, Guoyu Zuo
doaj   +1 more source

Evolutionary Computation Methods and their applications in Statistics

open access: yesStatistica, 2013
A brief discussion of the genesis of evolutionary computation methods, their relationship to artificial intelligence, and the contribution of genetics and Darwin’s theory of natural evolution is provided.
Francesco Battaglia
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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