Results 71 to 80 of about 2,645,282 (301)

Rapid diversification associated with a macroevolutionary pulse of developmental plasticity

eLife, 2015
Developmental plasticity has been proposed to facilitate phenotypic diversification in plants and animals, but the macroevolutionary potential of plastic traits remains to be objectively tested.
Vladislav Susoy, Erik J Ragsdale, Natsumi Kanzaki, Ralf J Sommer   +3 more
doaj   +1 more source

Michael Akam and the rise of evolutionary developmental biology

The International Journal of Developmental Biology, 2009
Michael Akam has been awarded the 2007 Kowalevsky medal for his many research accomplishments in the area of evolutionary developmental biology. We highlight three tributaries of Michaels contribution to evolutionary developmental biology. First, he has made major contributions to our understanding of development of the fruit fly, Drosophila ...
Stern, David L., Hoang, Rachel E.
openaire   +4 more sources

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Semen promotes oocyte development in Sebastes schlegelii elucidating ovarian development dynamics in live-bearing fish

iScience
Summary: In some vertebrates and invertebrates, semen release factors affecting female physiology and behavior. Here, we report that semen delivered to females is potentially beneficial for promoting oocyte development in a viviparous teleost, Sebastes ...
Fengyan Zhang, Weihao Song, Ruiyan Yang, Chaofan Jin, Yuheng Xie, Yiyang Shen, Xiangyu Gao, Hao Sun, Tianci Nie, Xinlu Yue, Zongcheng Song, Jie Qi, Quanqi Zhang, Yan He   +13 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Sexual maturation and smoltification in domesticated Atlantic salmon (Salmo salar L.) – is there a developmental conflict? [PDF]

, 2018
We present data from two experiments that examined how the developmental processes of smoltification and sexual maturation proceed in parallel in domesticated Atlantic salmon.
Andersson, Eva, Hansen, Tom Johnny, Sub Developmental Biology, Schulz, Rüdiger W., Nilsen, Tom Ole, Schulz, Rüdiger, Fjelldal, Per Gunnar, Nilsen, Tom O., Norberg, Birgitta, Developmental Biology   +9 more
core   +2 more sources

From the feces to the genome: a guideline for the isolation and preservation of Strongyloides stercoralis in the field for genetic and genomic analysis of individual worms

Parasites & Vectors, 2019
Strongyloidiasis is a soil-borne helminthiasis, which, in spite of the up to 370 million people currently estimated to be infected with its causing agent, the nematode Strongyloides stercoralis, is frequently overlooked.
Siyu Zhou, Dorothee Harbecke, Adrian Streit   +2 more
doaj   +1 more source

Convergent evolution of small molecule pheromones in Pristionchus nematodes

eLife, 2020
The small molecules that mediate chemical communication between nematodes—so-called ‘nematode-derived-modular-metabolites’ (NDMMs)—are of major interest because of their ability to regulate development, behavior, and life-history.
Chuanfu Dong, Cameron J Weadick, Vincent Truffault, Ralf J Sommer   +3 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source