Results 51 to 60 of about 38,842 (262)
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Foundations of Ecological and Evolutionary Change
Biological evolution is realised through the same mechanisms of birth and death that underlie change in population density. The deep interdependence between ecology and evolution is well established, and recent models focus on integrating eco ...
A. Bradley Duthie, Victor J. Luque
doaj +1 more source
Mean field limits of co-evolutionary signed heterogeneous networks
Many science phenomena are modelled as interacting particle systems (IPS) coupled on static networks. In reality, network connections are far more dynamic.
Marios Antonios Gkogkas +2 more
doaj +1 more source
Sexual imprinting leads to speciation in locally adapted populations
Sexual imprinting is widespread in birds and other species but its existence requires explanation. Our results suggest that sexual imprinting leads to speciation in locally‐adapted populations if a neutral mating cue—e.g., novel plumage coloration—arises
Richard M. Sibly, Robert N. Curnow
doaj +1 more source
An Evolutionary approach for solving Shrödinger Equation
The purpose of this paper is to present a method of solving the Shrödinger Equation (SE) by Genetic Algorithms and Grammatical Evolution. The method forms generations of trial solutions expressed in an analytical form. We illustrate the effectiveness of this method providing, for example, the results of its application to a quantum system minimal ...
Khalid Jebari +2 more
openaire +2 more sources
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
A spin stabilized satellite reorientation maneuver in the inertial space is investigated. Spin axis pointing and nutation damping magnetic attitude control algorithms are utilized.
Dmitry Roldugin, Mikhail Ovchinnikov
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Generalized solutions describing singularity interaction
We present a new method for constructing solutions to nonlinear evolutionary equations describing the propagation and interaction of nonlinear waves.
V. G. Danilov
doaj +1 more source
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source

