Results 81 to 90 of about 2,976,525 (341)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Dynamics of Intersexual Dominance and Adult Sex- Ratio in Wild Vervet Monkeys

open access: yesFrontiers in Psychology, 2020
Intersexual dominance relations are important for female mammals, because of their consequences for accessing food and for the degree of sexual control females experience from males.
Charlotte Korinna Hemelrijk   +6 more
doaj   +1 more source

Evolutionary Dynamics of Biological Games [PDF]

open access: yesScience, 2004
Darwinian dynamics based on mutation and selection form the core of mathematical models for adaptation and coevolution of biological populations. The evolutionary outcome is often not a fitness-maximizing equilibrium but can include oscillations and chaos.
Nowak, M.A., Sigmund, K.
openaire   +5 more sources

Notes on Evolutionary Game Dynamics [PDF]

open access: yes, 2004
This paper focuses on the mathematical core of evolutionary game dynamics. The biologist Maynard Smith showed that game theory can be applied successfully in biology.
TAKEUCHI, Hiroshi   +2 more
core  

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Comparing equilibria for game theoretic and evolutionary bargaining models

open access: yes, 2003
Game-theoretic models of bargaining are typically based on the assumption that players have perfect rationality and that they always play an equilibrium strategy.
Jennings, N. R.   +5 more
core   +1 more source

Analysis of long-term strategies of riparian countries in transboundary river basins

open access: yesScientific Reports, 2021
Transboundary river basins give rise to complex water-sharing decision making that can be analyzed as a game in the sense of dynamic game theory, as done in this work.
Fahimeh Mirzaei-Nodoushan   +3 more
doaj   +1 more source

PHASE TRANSITION IN EVOLUTIONARY GAMES [PDF]

open access: yesInternational Journal of Modern Physics A, 1999
The evolution of cooperative behavior is studied in the deterministic version of the Prisoners' Dilemma on a two-dimensional lattice. The payoff parameter is set at the critical region 1.8<b<2.0, where clusters of cooperators are formed in all spatial sizes.
Cao, Zhen, Hwa, Rudolph C.
openaire   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Poverty eradication: the need for good citizenship

open access: yesActa Academica, 2003
This paper makes use of game theory to argue that poverty and inequality can be understood as the outcome of a repeated game in which the players are caught in a poverty trap, or “prisoners’ dilemma”. They can escape this dilemma by means of cooperation
Wim Naudé
doaj   +3 more sources

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