Results 51 to 60 of about 235,286 (321)

Basic Evolutionary Approach to the Traveling Salesman Problem

open access: yesU.Porto Journal of Engineering, 2015
Evolutionary programming (EP) is a metaheuristic method developed as an alternative approach to artificial intelligence. The aim of this paper is to bring an introduction to EP algorithms through the implementation of the basic D. B. Fogel’s Evolutionary
Débora Regina de São José   +1 more
doaj   +1 more source

Programming adaptive laboratory evolution of 4-hydroxyisoleucine production driven by a lysine biosensor in Corynebacterium glutamicum

open access: yesAMB Express, 2021
4-Hydroxyisoleucine (4-HIL) is a promising drug for treating diabetes. In our previous study, 4-HIL was synthesized from self-produced L-isoleucine (Ile) in Corynebacterium glutamicum by expressing an Ile dioxygenase gene.
Xinping Yu   +4 more
doaj   +1 more source

The influence of mutation on population dynamics in multiobjective genetic programming [PDF]

open access: yes, 2010
Using multiobjective genetic programming with a complexity objective to overcome tree bloat is usually very successful but can sometimes lead to undesirable collapse of the population to all single-node trees.
Badran, K., Rockett, P.I.
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

UTILISATION OF EVOLUTION ALGORITHM IN PRODUCTION LAYOUT DESIGN [PDF]

open access: yesApplied Computer Science, 2017
The need for flexibility of layout planning puts higher requirements for uti-lisation of layout and location problem solving methods. Classical methods, like linear programming, dynamic programming or conventional heuristics are being replaced by ...
Martin KRAJČOVIČ, Patrik GRZNÁR
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

An evolutionary algorithm based on approximation method and related techniques for solving bilevel programming problems.

open access: yesPLoS ONE, 2022
In the engineering and economic management fields, optimisation models frequently involve different decision-making levels. These are known as multi-level optimisation problems.
Yuhui Liu   +3 more
doaj   +1 more source

EC-KitY: Evolutionary computation tool kit in Python with seamless machine learning integration

open access: yesSoftwareX, 2023
EC-KitY is a comprehensive Python library for doing evolutionary computation (EC), licensed under the BSD 3-Clause License, and compatible with scikit-learn.
Moshe Sipper   +3 more
doaj   +1 more source

A note on evolutionary stochastic portfolio optimization and probabilistic constraints [PDF]

open access: yes, 2010
In this note, we extend an evolutionary stochastic portfolio optimization framework to include probabilistic constraints. Both the stochastic programming-based modeling environment as well as the evolutionary optimization environment are ideally suited ...
Hochreiter, Ronald
core  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

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