Results 121 to 130 of about 604,094 (289)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Lineage-specific variation in the evolutionary stability of coral photosymbiosis. [PDF]
Sci Adv, 2021 Gault JA, Bentlage B, Huang D, Kerr AM.
europepmc +1 more source
On the Evolutionary Stability of Bargaining Inefficiency [PDF]
Bargaining; game theory; efficiency; evolutionary ...
Poulsen, Anders
core
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Methods for measuring the evolutionary stability of engineered genomes to improve their longevity. [PDF]
Synth Biol (Oxf), 2021 Nuismer SL +4 more
europepmc +1 more source
Convergence in Finite Cournot Oligopoly with Social and Individual Learning [PDF]
Convergence to Nash equilibrium in Cournot oligopoly is a problem that recurrently arises as a subject of study in economics. The development of evolutionary game theory has provided an equilibrium concept more directly connected with adjustment dynamics
Murat YILDIZOGLU (GREThA) +1 more
core
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Aposematic signalling in prey-predator systems: determining evolutionary stability when prey populations consist of a single species. [PDF]
J Math Biol, 2022 Scaramangas A, Broom M.
europepmc +1 more source
Finite-Population "Mass-Action" and Evolutionary Stability [PDF]
Nash proposed an interpretation of mixed strategies as the average pure-strategy play of a population of players randomly matched to play a normal-form game.
Axel Bernergard, Karl Wärneryd
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source