Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
On inferring evolutionary stability in finite populations using infinite population models. [PDF]
J Math Biol, 2021 Molina C, Earn DJD.
europepmc +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Stability of networked evolutionary games with payoff perturbation
IET Control Theory & ApplicationsIn networked evolutionary games (NEGs), some elements in the payoff matrix of players may change due to environmental factors. In this article, the stability of NEGs with payoff perturbation is studied using the semi‐tensor product (STP) of matrices, and
Ziyun Wang, Xiaoyu Zhao, Shihua Fu
doaj +1 more source
Aposematic signalling in prey-predator systems: determining evolutionary stability when prey populations consist of a single species. [PDF]
J Math Biol, 2022 Scaramangas A, Broom M.
europepmc +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Evolutionary stability: social convention, aggression, and cycles [Game theory]
, 2014 Presents a class about the idea of evolutionary stability and the evolution of social conventions.Consider games that involve aggressive (Hawk) and passive (Dove) strategies, finding that sometimes, evolutionary populations are mixed.
Polak, Ben
core
MathematicsWith the frequent occurrence of financial risks, financial innovation supervision has become an important research issue, and excellent regulatory strategies are of great significance to maintain the stability and sustainable development of financial ...
Mengzhu Xu +3 more
doaj +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Inbreeding, male viability, and the remarkable evolutionary stability of the aphid X chromosome. [PDF]
Heredity (Edinb), 2021 Roy SW.
europepmc +1 more source