Results 121 to 130 of about 192,884 (311)

Generic evolutionary design

Generic evolutionary design means the creation of a range of different designs by evolution. This paper introduces generic evolutionary design by a computer, describing a system capable of the evolution of a wide range of solid object designs from ...
Wakefield, Jonathan P., Bentley, Peter J.   +1 more
core  

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

Evolutionary Techniques for Parametric WCET Analysis.

, 2012
Estimating the worst-case execution time (WCET) of real-time programs is pivotal in their verification. WCET estimation either yields a numeric value that represents the maximum execution time of the program when executed on a specific hardware platform; or yields a parametric expression in the form of some function of the input which when instantiated
openaire   +3 more sources

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Evolutionary algorithms in artificial intelligence: a comparative study through applications [PDF]

, 1994
For many years research in artificial intelligence followed a symbolic paradigm which required a level of knowledge described in terms of rules. More recently subsymbolic approaches have been adopted as a suitable means for studying many problems.
Nettleton, David John, Nettleton, D.J
core  

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Nuclear environmental DNA resolves fine-scale population genetic structure in an aquatic habitat

iScience
Summary: There is considerable potential for nuclear genomic material in environmental DNA (eDNA) to inform us of population genetic structure within aquatic species.
Zifang Liu, Mary A. Kishe, Nestory P. Gabagambi, Asilatu H. Shechonge, Benjamin P. Ngatunga, Katie Smith, Andrew D. Saxon, Alan G. Hudson, Tyler Linderoth, George F. Turner, Rupert A. Collins, Martin J. Genner   +11 more
doaj   +1 more source

Why is economic geography an evolutionary science? [PDF]

During the past two decades, evolutionary economics has emerged as one of the innovative fields of research in economics, and in particular in the fields of the economics of technical change and theory of the firm (Nelson and Winter 1982; Dosi et al ...
Boschma, Ron, Frenken, Koen
core  

Evolutionary design using grammatical evolution and shape grammars : designing a shelter

, 2010
A new evolutionary design tool is presented, which uses shape grammars and a grammar-based form of evolutionary computation, grammatical evolution (GE).
John Mark Swafford, Swafford, John Mark, James McDermott, Hemberg, Erik, Michael O'Neill, Brabazon, Anthony, Ciaran McNally, Martin Hemberg, McDermott, James, Hemberg, Martin, Byrne, Jonathan, Erik Hemberg, Anthony Brabazon, Elizabeth Shotton, O\u27Neill, Michael, Jonathan Byrne, O'Neill, Michael, McNally, Ciaran, Shotton, Elizabeth   +18 more
core   +1 more source