Results 101 to 110 of about 192,884 (311)
, 2015 Gradient methods and their value in single-objective, real-valued optimization are well-established. As such, they play a key role in tackling real-world, hard optimization problems such as deformable image registration (DIR).
Sonke, Jan-Jakob +6 more
core +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Improving the Giant-Armadillo Optimization Method
AnalyticsGlobal optimization is widely adopted presently in a variety of practical and scientific problems. In this context, a group of widely used techniques are evolutionary techniques.
Glykeria Kyrou +2 more
doaj +1 more source
Optimization Techniques and Evolutionary Algorithms
, 2021 The field of artificial intelligence (AI) continues to evolve at an extraordinary pace, and at the heart of many AI breakthroughs lies the discipline of opti- mization. This book, Optimization Techniques and Evolutionary Algorithms, was written to address the growing need for a clear and practical introduction to optimization, especially as it applies ...
openaire +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Overview of a Generic Evolutionary Design System
, 1996 This paper presents an overview of a generic evolutionary design system. The system uses a hybrid 'steady-state' multiobjective genetic algorithm with an explicit mapping stage between genotypes and phenotypes to evolve designs.
Wakefield, Jonathan P. +1 more
core
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
The emerging empirics of evolutionary economic geography [PDF]
Following last decadeÕs programmatic papers on Evolutionary Economic Geography, we report on recent empirical advances and how this empirical work can be positioned vis-ˆ-vis other strands of research in economic geography.
Koen Frenken, Ron Boschma
core +2 more sources
A Comparison of Evolutionary Computation Techniques for IIR Model Identification
Journal of Applied Mathematics, 2014 System identification is a complex optimization problem which has recently attracted the attention in the field of science and engineering. In particular, the use of infinite impulse response (IIR) models for identification is preferred over their ...
Erik Cuevas +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source