Results 61 to 70 of about 12,015 (284)
«On the Origin of Species»: Didactic transposition to the curriculum and Portuguese science textbooks (1859-1959) [PDF]
, 2017 This research aimed to contribute to the history of the teaching of Darwinism in the Portuguese curriculum from 1859 to 1959. To this end, it was analysed the didactic transposition of the book On the Origin of Species for standards and textbooks of ...
Cavadas, Bento
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Mathematical Knowledge, the Analytic Method, and Naturalism [PDF]
, 2018 This chapter tries to answer the following question: How should we conceive of the method of mathematics, if we take a naturalist stance? The problem arises since mathematical knowledge is regarded as the paradigm of certain knowledge, because ...
Sterpetti, Fabio
core +1 more source
Foucauldian Peacekeeping: On the Dispersion of Power and the Futility of Change [PDF]
, 2009 Foucault is widely known for the radical nature of his work, for his idiosyncratic approach to history, and for his reconfiguration of the concept of power. Curiously though, his conceptions of history and power might act to undermine their potential to
Allen, Ansgar
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Dušan Bandić – context, opus, significance
Etnoantropološki Problemi, 2014 The scientific opus of Dušan Bandić is viewed through the context and time frame in which he started researching folk religion in order to, through the analysis of his most important texts, arrive at the conclusion about the importance of his opus for ...
Ivan Kovačević
doaj +1 more source
Materialism, Idealism and the Onto-Epistemological Roots of Geography [PDF]
, 2017 The present article has as proposal the discussion of the philosophical categories of Idealism and Materialism in the Geographical thought. Starting from the assumption that the knowledge is a fact, we explicit our onto-epistemological basis by a dialog ...
Paiva, Mikhael Lemos
core +3 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source