Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Exploring Generative Adversarial Networks for Text-to-Image Generation with Evolution Strategies [PDF]
Víctor Costa +3 more
openalex +1 more source
Dušan Bandić – context, opus, significance
The scientific opus of Dušan Bandić is viewed through the context and time frame in which he started researching folk religion in order to, through the analysis of his most important texts, arrive at the conclusion about the importance of his opus for ...
Ivan Kovačević
doaj +1 more source
Materialism, Idealism and the Onto-Epistemological Roots of Geography [PDF]
The present article has as proposal the discussion of the philosophical categories of Idealism and Materialism in the Geographical thought. Starting from the assumption that the knowledge is a fact, we explicit our onto-epistemological basis by a dialog ...
Paiva, Mikhael Lemos
core +3 more sources
Evolution of solar wind sources and coronal rotation driven by the cyclic variation of the Sun's large-scale magnetic field [PDF]
Adam J. Finley, A. S. Brun
openalex +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
American Medical and Intellectual Reaction to African Health Issues, 1850-1960: From Racialism to Cross-Cultural Medicine [PDF]
During recent decades, social scientists, particularly anthropologists, sociologists and medical historians, have looked increasingly at how social and cultural factors inform a society\u27s medical community and vice-versa.
McBride, David
core +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Regional science at the turn of the century: Reflections on its epistemological status [PDF]
As a contribution to the current debate on the state-of-the art of regional science, this paper presents some reflections on the epistemological and methodological status of the discipline as we approach the turn of the century.
Angela Spence, Giovanni A. Rabino
core
«On the Origin of Species»: Didactic transposition to the curriculum and Portuguese science textbooks (1859-1959) [PDF]
This research aimed to contribute to the history of the teaching of Darwinism in the Portuguese curriculum from 1859 to 1959. To this end, it was analysed the didactic transposition of the book On the Origin of Species for standards and textbooks of ...
Cavadas, Bento
core +2 more sources

