Results 81 to 90 of about 656 (250)

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Data on the identification of microsatellite markers in Eisenia fetida and Eisenia andrei. [PDF]

open access: yesData Brief, 2022
Jaskulak M   +6 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Evolução e desígnio em Hayek

open access: yesDados: Revista de Ciências Sociais, 1999
In an examination of Hayek?s social philosophy, the article seeks to distinguish between socio-epistemological arguments, which postulate the radical ignorance of social actors, and the conservative political conclusions usually associated with Hayek?s ...
Kerstenetzky Celia Lessa
doaj  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

L’evoluzione dei segnali sessuali nell’uomo: tattiche di comunicazione verbale e non verbale durante il corteggiamento

open access: yesJournal of Educational, Cultural and Psychological Studies, 2012
The Evolution of Sexual Signals in Humans: Direct Verbal and Nonverbal Tactics of Communication During Courtship In human evolutionary history, men and women have dealt with different adaptive aspects in the sexual domain.
Roberta Carbone, Angelo Tartabini
doaj  

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

La poésie de l’élan vital avant Bergson

open access: yesArts et Savoirs
Bergson’s image-concept of “élan vital” has its precursors in nineteenth-century French poetry. Prompted by reflections on the living world, especially evolutionism, poetry (particularly in the genre of scientific poetry) sought to articulate a new ...
Nicolas Wanlin
doaj   +1 more source

[The correlation of medicine and evolutionism - the evolutionism in Metchinikov's medical thought].

open access: yesUi sahak, 2000
The correlation of medicine and evolutionism was negligent in the history of science. This article analyzes the correlation of medicine and evolutionism in Metchinikov's medical thought. Metchinikov was concerned about the correlation of medicine and evolutionism. In the late nineteenth century when Metchinikov was engaged in his work, the evolutionism
openaire   +1 more source

Home - About - Disclaimer - Privacy