Results 101 to 110 of about 10,925 (230)

Rib Ewing Sarcomas in Children and Young Adults: A Large National Retrospective Series

open access: yesPediatric Blood &Cancer, Volume 73, Issue 4, April 2026.
ABSTRACT Background and Purpose Ewing sarcoma (ES) is the most prevalent malignant thoracic tumor in childhood and young adults. This study reports the outcome of a national cohort treated in an international prospective trial for a localized rib ES, with a long follow‐up.
Audrey Claren   +14 more
wiley   +1 more source

Efficacy and Safety of Donor Lymphocyte Infusion After Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients

open access: yesEuropean Journal of Haematology, Volume 116, Issue 4, Page 443-449, April 2026.
ABSTRACT This retrospective study evaluates the efficacy and safety of donor lymphocyte infusion (DLI) after allogeneic hematopoietic stem cell transplantation (HSCT) in children. We describe the long‐term use of preemptive, prophylactic, and therapeutic DLI with a gradual dose increase in half‐log increments.
Dinah Walther   +7 more
wiley   +1 more source

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

open access: yesPediatric Blood &Cancer, Volume 73, Issue 3, March 2026.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar   +8 more
wiley   +1 more source

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

open access: yesPediatric Blood &Cancer, Volume 73, Issue 3, March 2026.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis   +13 more
wiley   +1 more source

The epidemiology of bone cancer in 0 - 39 year olds in northern England, 1981 - 2002 [PDF]

open access: yes, 2010
Background: There is a paucity of recent epidemiological data on bone cancers. The aim of this study was to describe incidence and survival patterns for bone cancers diagnosed during 1981 - 2002.Methods: Cases aged 0 - 39 years (236 osteosarcomas, 166 ...
Rachel Eyre   +8 more
core   +1 more source

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

open access: yesPediatric Blood &Cancer, Volume 73, Issue 3, March 2026.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack   +12 more
wiley   +1 more source

Retrotracheal Extraskeletal Ewing’s Sarcoma: Case Report and Discussion on Airway Management

open access: yesTurkish Archives of Otorhinolaryngology, 2017
Extraskeletal Ewing’s sarcoma is a rare tumor, and the management of airway compromise in case of cervical Ewing’s sarcoma has not been established. This report describes the case of a patient with retrotracheal Ewing’s sarcoma and discusses a successful
Graeme Van Der Meer   +4 more
doaj   +1 more source

Ewing's sarcoma [PDF]

open access: yesCancer, 1952
L J, McCORMACK   +2 more
openaire   +2 more sources

Impact of tissue staining and scanner variation on the performance of pathology foundation models: a study of sarcomas and their mimics

open access: yesThe Journal of Pathology: Clinical Research, Volume 12, Issue 2, March 2026.
Abstract Histopathological analysis is considered the gold standard for the diagnosis and prognostication of cancer. Recent advances in AI, driven by large‐scale digitisation and pan‐cancer foundation models, are opening new opportunities for clinical integration.
Binghao Chai   +74 more
wiley   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang   +7 more
wiley   +1 more source

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