Results 81 to 90 of about 5,957 (165)
The Journal of Physiology, EarlyView.Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani +5 more
wiley +1 more source
Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
An unusual biconvex epidural lesion: acutely presenting extraosseous intracranial Ewing’s sarcoma
Chinese Neurosurgical Journal, 2018 Background Ewing’s sarcoma family of tumors consists of small round cell neoplasms, inclusive of primitive neuroectodermal tumor (PNET), Askin’s tumor, and PNET of the bone.
Kalimullah Jan +2 more
doaj +1 more source
Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.Preclinical models for sarcoma that preserve tumour biology are urgently needed to advance mechanistic understanding and functional precision oncology. 29 early‐passage patient‐derived sarcoma cell (PDC) cultures from 19 patients, representing 11 sarcoma subtypes were established and extensively characterized.
Stefanie Gijsels +19 more
wiley +1 more source
Medicinal Research Reviews, Volume 46, Issue 4, Page 989-1004, July 2026.ABSTRACT CRISPR‐Cas9 genome‐wide screening has been instrumental towards identifying novel targets for drug discovery in cancer research. However, much of this research has centred specifically on adult cancers, with paediatric cancers being underserviced by current research and screening.
Steven He +2 more
wiley +1 more source
Retrotracheal Extraskeletal Ewing’s Sarcoma: Case Report and Discussion on Airway Management
Turkish Archives of Otorhinolaryngology, 2017 Extraskeletal Ewing’s sarcoma is a rare tumor, and the management of airway compromise in case of cervical Ewing’s sarcoma has not been established. This report describes the case of a patient with retrotracheal Ewing’s sarcoma and discusses a successful
Graeme Van Der Meer +4 more
doaj +1 more source
Chemotherapy in Ewing’s sarcoma
Indian Journal of Orthopaedics, 2010 Ewing's sarcoma constitutes three per cent of all pediatric malignancies. Ewing's sarcoma has generally been more responsive to chemotherapy than adult-type sarcomas, and chemotherapy is now recommended for all patients with this disease. It is essential to integrate local control measures in the form of surgery and/or radiotherapy at the appropriate ...
Jain, Sandeep, Kapoor, Gauri
openaire +3 more sources
Neovascularization in Ewing’s sarcoma
Neoplasma, 2018 Ewing's sarcoma is the second most common bone malignancy in adolescents and young adults after osteosarcoma. Similar to other solid tumors, Ewing's sarcomas require an adequate vascular supply to grow and survive. The development and maintenance of vascular supply is accomplished via three main mechanisms; angiogenesis, vasculogenesis, and tumor cell ...
Mavrogenis, A.F. +4 more
openaire +4 more sources
Case Reports in Neurological Medicine, 2016 Background. Extraosseous Ewing’s sarcoma in the spinal epidural space is a rare malignancy, especially in adults. Case Presentation. A 40-year-old male presented with back pain and urinary hesitancy.
Mark Bustoros +8 more
doaj +1 more source