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Advances in molecular pathology of Ewing sarcoma [PDF]
Ewing sarcoma is a rare malignant small round cell mesenchymal neoplasm with a characteristic FET family-ETS family fusion gene, and is classified as undifferentiated small round cell sarcoma in the fifth revision of the WHO Classification of Tumors of ...
LIU Hengan, WANG Chaofu
doaj +2 more sources
Extraosseous Ewing sarcoma of the pancreas: a case report [PDF]
Extraosseous Ewing sarcoma is a rare and aggressive malignancy belonging to the Ewing sarcoma family of tumors, primarily affecting soft tissues such as the pelvis, retroperitoneum, and chest wall.
Neslihan Nisa Gecici +3 more
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Ewing sarcoma genomics and recent therapeutic advancements
Ewing sarcomas are highly heterogenous mesenchymal tumors that develop in bone or soft tissue and primarily affect children, teenagers, and young adults. After osteosarcoma, it is the second most common malignant bone sarcoma.
Manisha Chavan +6 more
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Cutaneous Ewing Sarcoma and Ewing Sarcoma of the Bone: Distinct Diseases [PDF]
Ewing sarcoma is an aggressive mesenchymal malignancy. It is the second most common bone tumor among children and adolescents and less commonly presents as a soft tissue or primary skin lesion.
Montreh Tavakkoli, Lisa Mueller
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SPOP and OTUD7A Control EWS–FLI1 Protein Stability to Govern Ewing Sarcoma Growth
Chromosomal translocation results in development of an Ewing sarcoma breakpoint region 1‐Friend leukemia integration 1 (EWS–FLI1) fusion oncogene in the majority of Ewing sarcoma.
Ying Wang +2 more
exaly +2 more sources
Ewing sarcoma of the pelvis: Clinical features and overall survival,
Introduction: Primary Ewing Sarcoma of Bone is a malignancy whose treatment requires both systemic chemotherapy and local control through surgical resection and/or radiation. Ewing Sarcoma of the pelvis has been noted to confer a worse prognosis relative
Jeffrey Mark Brown +4 more
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Ewing sarcoma is the second most frequent bone tumour of childhood and adolescence that can also arise in soft tissue. Ewing sarcoma is a highly aggressive cancer, with a survival of 70–80% for patients with standard-risk and localized disease and ~30 ...
Álava, Enrique de +8 more
core +5 more sources
Ewing sarcomas are characterized by oncogenic ews/ets translocations. However, these oncofusions do not determine the outcome. Patient fate is determined by metastasis, and the complex spreading process is far from being completely understood.
Vanhoenacker, Filip M. +3 more
core +3 more sources
Characteristics of human Ewing/PNET sarcoma models
Ewing/PNET (peripheral neuroepithelioma) tumors are rare aggressive bone sarcomas occurring in young people. Rare-disease clinical trials can require global collaborations and many years. In vivo models that as accurately as possible reflect the clinical
Teicher Beverly +5 more
doaj +1 more source
Primary Ewing sarcoma of the kidney: a symptomatic presentation and review of the literature
The objective of this review is to discuss the unique nature of primary renal Ewing sarcoma, including incidence, presentation and management. We also report on a common pattern of presentation, consisting of acute flank pain mimicking a renal stone ...
Jorge L Lockhart, Alejandro R Rodríguez
exaly +2 more sources

