Results 11 to 20 of about 244,564 (198)
Ewing sarcoma genomics and recent therapeutic advancements
Pediatric Hematology Oncology Journal, 2023 Ewing sarcomas are highly heterogenous mesenchymal tumors that develop in bone or soft tissue and primarily affect children, teenagers, and young adults. After osteosarcoma, it is the second most common malignant bone sarcoma.
Manisha Chavan +6 more
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Advances in molecular pathology of Ewing sarcoma [PDF]
Zhenduanxue lilun yu shijian, 2023 Ewing sarcoma is a rare malignant small round cell mesenchymal neoplasm with a characteristic FET family-ETS family fusion gene, and is classified as undifferentiated small round cell sarcoma in the fifth revision of the WHO Classification of Tumors of ...
LIU Hengan, WANG Chaofu
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Extraosseous Ewing sarcoma of the pancreas: a case report [PDF]
Korean Journal of Clinical Oncology, 2023 Extraosseous Ewing sarcoma is a rare and aggressive malignancy belonging to the Ewing sarcoma family of tumors, primarily affecting soft tissues such as the pelvis, retroperitoneum, and chest wall.
Neslihan Nisa Gecici +3 more
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Targeting GPX4 and FSP1 to exploit ferroptotic vulnerability in Ewing sarcoma [PDF]
Frontiers in OncologyEwing sarcoma tumors are defined by chromosomal translocations fusing EWSR1 to ETS family genes, most commonly FLI1. The resulting EWS::FLI1 fusion oncoprotein drives tumorigenesis while simultaneously generating unique metabolic and molecular ...
Mian T. Mhindu +4 more
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Clinical activity of pazopanib in metastatic extraosseous Ewing sarcoma
Rare Tumors, 2015 We report a response to pazopanib in a 69-year-old man with heavily pre-treated metastatic extraosseous Ewing sarcoma in addition to molecular profiling of his tumor.
Steven Attia +12 more
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Cutaneous Ewing Sarcoma and Ewing Sarcoma of the Bone: Distinct Diseases [PDF]
Case Reports in Oncology, 2018 Ewing sarcoma is an aggressive mesenchymal malignancy. It is the second most common bone tumor among children and adolescents and less commonly presents as a soft tissue or primary skin lesion.
Montreh Tavakkoli, Lisa Mueller
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Characteristics of human Ewing/PNET sarcoma models
Annals of Saudi Medicine, 2011 Ewing/PNET (peripheral neuroepithelioma) tumors are rare aggressive bone sarcomas occurring in young people. Rare-disease clinical trials can require global collaborations and many years. In vivo models that as accurately as possible reflect the clinical
Teicher Beverly +5 more
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Combined inhibition of CDK4/6 and PI3K pathways exhibit highly synergistic activity and translational potential in Ewing sarcoma [PDF]
Translational OncologyEwing sarcoma is a highly aggressive solid malignancy affecting children and young adults. Ewing sarcoma is driven primarily by EWSR1::FLI1, a fusion oncoprotein that has been notoriously difficult to target with traditional pharmacologic agents.
Helen F. Gloege +17 more
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Primary Ewing sarcoma of the pancreas: A rare extraosseous presentation [PDF]
Radiology Case ReportsEwing sarcoma is an aggressive neoplasm that is common among children and adolescents, most frequently affecting the pelvis and long bones. Although rare, Ewing sarcoma is known to also occur in extraosseous locations, affecting a broad range of soft ...
Elias Lugo-Fagundo, BS +3 more
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Bridged bicyclic carboxylic acids for treating osteosarcoma and Ewing sarcoma [PDF]
, 2023 The present invention provides a composition for use in a method of treating osteosarcoma, Ewing sarcoma and/or a metastatic cancer originating from osteosarcoma or Ewing sarcoma. The present invention also provides a method of treating a cancer selected
Fraser, William, Green, Darrell
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