Results 41 to 50 of about 24,471 (221)
Catching the driver mutations in Ewing sarcoma tumours: an in silico genomic analysis [PDF]
, 2019 OBJECTIVE: Ewing sarcoma (EWS) is a rare neuroectodermal-related malignancy affecting bones and soft tissues. The well-known hallmark of genomic alteration in EWS is gene fusion involving the Ewing Sarcoma Breakpoint Region 1 (EWSR1) gene.
M. Fawzy, A. Toreih, E. Toraih
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CA: A Cancer Journal for Clinicians, 1976 There are no known external causes of Ewing’ sarcoma, a form of bone cancer, although a small number of cases are linked to genetic abnormalities. This malignancy occurs with remarkable consistency in registry populations across Europe and the United States, including Los Angeles County. Few cases of it occur after age 30.
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Ewing's sarcoma of the calcaneum
Indian Journal of Medical and Paediatric Oncology, 2017 Ewing's sarcoma of the calcaneum is rare. Radiological features of this tumor can be misinterpreted as other benign bone tumors due to its rarity. The overall prognosis of Ewing's sarcoma of calcaneum is inferior compared to other sites of this tumor.
Sherif, P Ajmal, Santa, A
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Metastatic Ewing's sarcoma to the right ventricle [PDF]
, 2011 Ewing's sarcoma is a round cell neoplasm derived from neural crest cells that is part of the primitive neuroectodermal tumor (PNET) family. It is a rare, aggressive malignancy that affects young people, most commonly in the second decade of life.
Milliken, Jeffrey +5 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters +17 more
wiley +1 more source
Ewing′s sarcoma of the mandible
National Journal of Maxillofacial Surgery, 2011 Ewing's sarcoma is a malignant tumor of bones that primarily affects children and young adults. The true origin of this small round cell lesion still remains controversial. It was originally described by James Ewing in 1921 as arising from undifferentiated osseous mesenchymal cells; however, recent studies suggest that Ewing's tumor might be ...
Rao, B. H. Sripathi +3 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Local Tumor Control Affects Survival of Patients with Osteosarcoma and Ewing Sarcoma
Majalah Kedokteran BandungOsteosarcoma and Ewing sarcoma are the most common primary malignant bone tumors in children. This study aimed to analyze the characteristics of osteosarcoma and Ewing sarcoma patients at Dr.
Nur Suryawan +2 more
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Journal of Oral and Maxillofacial Pathology, 2009 Ewing's sarcoma is a malignant, small, round cell neoplasm that normally affects the long bones of the limbs or the pelvis. It is a relatively frequent malignant bone tumor in children. The occurrence of the primary tumor in the facial region is approximately 2%, with most of the cases affecting the mandible.
Deshingkar, SA +2 more
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Advanced Science, EarlyView.MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou +21 more
wiley +1 more source