Results 31 to 40 of about 24,471 (221)

Eltrombopag inhibits the proliferation of Ewing sarcoma cells via iron chelation and impaired DNA replication

BMC Cancer, 2020
Background The treatment of Ewing sarcoma, an aggressive bone and soft tissue sarcoma, is associated with suboptimal outcomes and significant side-effects.
Torin Waters, Kelli L. Goss, Stacia L. Koppenhafer, William W. Terry, David J. Gordon   +4 more
doaj   +1 more source

Repression of enhancer RNA PHLDA1 promotes tumorigenesis and progression of Ewing sarcoma via decreasing infiltrating T‐lymphocytes: A bioinformatic analysis

Frontiers in Genetics, 2022
Background: The molecular mechanisms of EWS-FLI-mediating target genes and downstream pathways may provide a new way in the targeted therapy of Ewing sarcoma.
Runzhi Huang, Runzhi Huang, Runzhi Huang, Dan Huang, Siqiao Wang, Shuyuan Xian, Yifan Liu, Minghao Jin, Xinkun Zhang, Shaofeng Chen, Xi Yue, Wei Zhang, Jianyu Lu, Huizhen Liu, Zongqiang Huang, Zongqiang Huang, Hao Zhang, Huabin Yin   +17 more
doaj   +1 more source

Irinotecan plus temozolomide in relapsed Ewing sarcoma: an integrated analysis of retrospective studies

BMC Cancer, 2022
Highlights 1. Nearly 44% of relapsed Ewing sarcoma patients achieved an ORR after IT treatment. 2. Relapsed Ewing sarcoma treated with IT had an over 66% DCR. 3.
Bi-Cheng Wang, Bo-Ya Xiao, Guo-He Lin
doaj   +1 more source

Wolf in sheep's clothing: Primary orbital Ewing sarcoma in a child masquerading as internal angular dermoid

Oman Journal of Ophthalmology, 2022
Ewing sarcoma is one of the rare, highly malignant neuroectodermal tumors frequently involving bones. Primary orbital Ewing sarcoma is extremely uncommon.
Teena Mariet Mendonca, Harsha Prasada Lashkari, Pooja K Suresh, Rahul Kondaveti, Faraz Ali, Gladys R Rodrigues   +5 more
doaj   +1 more source

Genome-wide functional perturbation of human microsatellite repeats using engineered zinc finger transcription factors

Cell Genomics, 2022
Summary: Repeat elements can be dysregulated at a genome-wide scale in human diseases. For example, in Ewing sarcoma, hundreds of inert GGAA repeats can be converted into active enhancers when bound by EWS-FLI1.
Y. Esther Tak, Gaylor Boulay, Lukuo Lee, Sowmya Iyer, Nicholas T. Perry, Hayley T. Schultz, Sara P. Garcia, Liliane Broye, Joy E. Horng, Shruthi Rengarajan, Beverly Naigles, Angela Volorio, Jeffry D. Sander, Jingyi Gong, Nicolò Riggi, J. Keith Joung, Miguel N. Rivera   +16 more
doaj   +1 more source

ESF-EMBO symposium "molecular biology and innovative therapies in sarcomas of childhood and adolescence" Sept 29–Oct 4, Polonia Castle Pultusk, Poland [PDF]

, 2013
Rhabdomyosarcoma (RMS) and Ewing sarcoma (ES) are among the most common pediatric sarcomas (Arndt et al., 2012). Despite sarcomas representing a highly heterogeneous group of tumors, ES and alveolar RMS (ARMS) typically share one common genetic ...
Beat W. Schäfer, Simone eFulda, Heinrich eKovar, Heinrich Kovar, Beat W Schäfer, Koscielniak, Ewa, Ewa eKoscielniak, Fulda, Simone, Schäfer, Beat W, Kovar, Heinrich, Simone Fulda, Schäfer, Beat W., Ewa Koscielniak   +12 more
core   +1 more source

Ewing sarcoma of larynx: A rare case in a 5-year-old boy

, 2020
Ewing Sarcoma of the head and neck region is an extremely rare entity. Treatment usually involves surgery, chemotherapy and radiotherapy in varying sequences. We present the third case to date of Ewing sarcoma of the larynx in a paediatric population.
Siddiqui, Moghira, Shayan Khalid Ghaloo, Pasha, Hamdan Ahmed, Moghira Iqbaluddin Siddiqui, Ud Din, Nasir, Wasif, Muhammad, Hamdan Ahmed Pasha, Muhammad Wasif, Khalid, Shayan, Nasir Ud Din   +9 more
core   +1 more source

Effect of Educational Guidelines on Mothers' Knowledge, Reported Practices, and Anxiety regarding their Children having Ewing Sarcoma [PDF]

Egyptian Journal of Health Care
Background: Ewing tumors, also called Ewing sarcomas, are a class of malignancies that originate in the surrounding soft tissues or bones and have a few characteristics as common.
Heba Boshra Shehata, Amal Abo El-Azm Abd El - Rahman Younis, Ohoud Youssef EL-Sheikh, Mai Nour Eldien Mohamed Mohamed Awad, Lamiaa Moustafa Elbosaty, Mariana Erian Shehata   +5 more
doaj   +1 more source

Gastric Ewing Sarcoma identified on a Meckel's scan

Radiology Case Reports, 2020
Ewing Sarcoma is a malignant small round blue cell tumor most commonly found in bones and soft tissues of the axial skeleton and extremities. The Ewing family of tumors, including peripheral neuroectodermal tumor, represent the second most common ...
Lavi Nissim, MD, Gerald Mandell, MD
doaj   +1 more source

Congenital extraskeletal Ewing′s sarcoma of chest wall - A rare case report

Indian Journal of Pathology and Microbiology, 2011
Congenital extraskeletal Ewing′s sarcoma or peripheral primitive neuroectodermal tumor is an extremely uncommon and invariably fatal tumor. We report a case of extraskeletal congenital Ewing′s sarcoma in a female fetus delivered at 34 weeks of gestation ...
Bhagyalakshmi Atla, B Satya Vara Prasad, K Satya Sri, Geeta Vandana   +3 more
doaj   +1 more source