Targeting GPX4 and FSP1 to exploit ferroptotic vulnerability in Ewing sarcoma [PDF]
Frontiers in OncologyEwing sarcoma tumors are defined by chromosomal translocations fusing EWSR1 to ETS family genes, most commonly FLI1. The resulting EWS::FLI1 fusion oncoprotein drives tumorigenesis while simultaneously generating unique metabolic and molecular ...
Mian T. Mhindu +4 more
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Primary Ewing sarcoma of the pancreas: A rare extraosseous presentation [PDF]
Radiology Case ReportsEwing sarcoma is an aggressive neoplasm that is common among children and adolescents, most frequently affecting the pelvis and long bones. Although rare, Ewing sarcoma is known to also occur in extraosseous locations, affecting a broad range of soft ...
Elias Lugo-Fagundo, BS +3 more
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Extraosseous Ewing sarcoma of the pancreas: a case report [PDF]
Korean Journal of Clinical Oncology, 2023 Extraosseous Ewing sarcoma is a rare and aggressive malignancy belonging to the Ewing sarcoma family of tumors, primarily affecting soft tissues such as the pelvis, retroperitoneum, and chest wall.
Neslihan Nisa Gecici +3 more
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Advances in molecular pathology of Ewing sarcoma [PDF]
Zhenduanxue lilun yu shijian, 2023 Ewing sarcoma is a rare malignant small round cell mesenchymal neoplasm with a characteristic FET family-ETS family fusion gene, and is classified as undifferentiated small round cell sarcoma in the fifth revision of the WHO Classification of Tumors of ...
LIU Hengan, WANG Chaofu
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Caregivers Awareness Regarding Health Care offered to their children with Ewing Sarcoma [PDF]
Egyptian Journal of Health Care, 2023 Background: Ewing sarcoma is a very aggressive malignancy tumor that requires complex multidisciplinary management. The aim of the study: Was to assess caregivers’ awareness regarding health care offered to their children with Ewing sarcoma.
Lamyaa Momtaz Mohamed +2 more
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Differentially expressed miRNAs in Ewing sarcoma compared to mesenchymal stem cells: low miR-31 expression with effects on proliferation and invasion. [PDF]
PLoS ONE, 2014 Ewing sarcoma, the second most common bone tumor in children and young adults, is an aggressive malignancy with a strong potential to metastasize. Ewing sarcoma is characterised by translocations encoding fusion transcription factors with an EWSR1 ...
Bianca Karnuth +8 more
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Bibliometric analysis of Ewing sarcoma from 1993 to 2022
BMC Cancer, 2023 Background Ewing sarcoma has attracted more attention in recent years but has yet to be bibliometrically analyzed. Hence, this study investigated the trend of Ewing sarcoma over the past 30 years with bibliometric analysis.
Guangtao Han, Ting Liu, Pengde Kang
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Ewing sarcoma genomics and recent therapeutic advancements
Pediatric Hematology Oncology Journal, 2023 Ewing sarcomas are highly heterogenous mesenchymal tumors that develop in bone or soft tissue and primarily affect children, teenagers, and young adults. After osteosarcoma, it is the second most common malignant bone sarcoma.
Manisha Chavan +6 more
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Ewing sarcoma with very late metastasis in the skull: a case report
Journal of Medical Case Reports, 2022 Background Ewing sarcoma is a malignant bone tumor; however, its prognosis has improved since the development of modern chemotherapy. Although Ewing sarcoma outcomes have improved, issues related to late complications, secondary malignant neoplasms, and ...
Ryota Hagihara +6 more
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Variable expression of PIK3R3 and PTEN in Ewing Sarcoma impacts oncogenic phenotypes. [PDF]
PLoS ONE, 2015 Ewing Sarcoma is an aggressive malignancy of bone and soft tissue affecting children and young adults. Ewing Sarcoma is driven by EWS/Ets fusion oncoproteins, which cause widespread alterations in gene expression in the cell.
Brian F Niemeyer +5 more
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