Results 11 to 20 of about 244,614 (241)
Clinical activity of pazopanib in metastatic extraosseous Ewing sarcoma
Rare Tumors, 2015 We report a response to pazopanib in a 69-year-old man with heavily pre-treated metastatic extraosseous Ewing sarcoma in addition to molecular profiling of his tumor.
Steven Attia +12 more
doaj +2 more sources
Cutaneous Ewing Sarcoma and Ewing Sarcoma of the Bone: Distinct Diseases [PDF]
Case Reports in Oncology, 2018 Ewing sarcoma is an aggressive mesenchymal malignancy. It is the second most common bone tumor among children and adolescents and less commonly presents as a soft tissue or primary skin lesion.
Montreh Tavakkoli, Lisa Mueller
doaj +2 more sources
Characteristics of human Ewing/PNET sarcoma models
Annals of Saudi Medicine, 2011 Ewing/PNET (peripheral neuroepithelioma) tumors are rare aggressive bone sarcomas occurring in young people. Rare-disease clinical trials can require global collaborations and many years. In vivo models that as accurately as possible reflect the clinical
Teicher Beverly +5 more
doaj +1 more source
New England Journal of Medicine, 2021 Ewing’s Sarcoma Ewing’s sarcoma, an aggressive cancer of bone and soft tissue, primarily affects children and young adults. A t(11;22) translocation is noted in 85 to 90% of cases.
Ludwig, Joseph A. +2 more
openaire +6 more sources
Bridged bicyclic carboxylic acids for treating osteosarcoma and Ewing sarcoma [PDF]
, 2023 The present invention provides a composition for use in a method of treating osteosarcoma, Ewing sarcoma and/or a metastatic cancer originating from osteosarcoma or Ewing sarcoma. The present invention also provides a method of treating a cancer selected
Fraser, William, Green, Darrell
core +3 more sources
Pediatric Blood & Cancer, 2021 AbstractEwing sarcoma is a rare tumor that requires complex multidisciplinary management. This report describes the general management and standard radiotherapy guidelines in both North America (Children's Oncology Group) and Europe (International Society of Pediatric Oncology).
Bree R. Eaton +6 more
openaire +2 more sources
Ewing Sarcoma Developed at the Site of Previous Mast Cell Proliferation [PDF]
, 2023 KIT gene mutations in Ewing sarcomas are rare; however, they are much more frequent in other neoplasms, namely mastocytosis. We describe a case of an adult male with a one-year duration of recurrent episodes of pain, swelling, and redness on the proximal
Rosendo, Eugénia +4 more
core +1 more source
CD44 Modulates Cell Migration and Invasion in Ewing Sarcoma Cells [PDF]
, 2023 The chimeric EWSR1::FLI1 transcription factor is the main oncogenic event in Ewing sarcoma. Recently, it has been proposed that EWSR1::FLI1 levels can fluctuate in Ewing sarcoma cells, giving rise to two cell populations.
Luis Chapado +23 more
core +1 more source
Ewing sarcoma of larynx: A rare case in a 5-year-old boy [PDF]
, 2020 Ewing Sarcoma of the head and neck region is an extremely rare entity. Treatment usually involves surgery, chemotherapy and radiotherapy in varying sequences. We present the third case to date of Ewing sarcoma of the larynx in a paediatric population.
Siddiqui, Moghira +9 more
core +1 more source
Therapeutic Potential of EWSR1-FLI1 Inactivation by CRISPR/Cas9 in Ewing Sarcoma [PDF]
, 2021 Factor de impacto: 6,639 Q1Ewing sarcoma is an aggressive bone cancer affecting children and young adults. The main molecular hallmark of Ewing sarcoma are chromosomal translocations that produce chimeric oncogenic transcription factors, the most ...
Moreno-Pelayo, Miguel Angel +26 more
core +1 more source