Results 21 to 30 of about 19,217 (182)

Ewing sarcoma genomics and recent therapeutic advancements

open access: yesPediatric Hematology Oncology Journal, 2023
Ewing sarcomas are highly heterogenous mesenchymal tumors that develop in bone or soft tissue and primarily affect children, teenagers, and young adults. After osteosarcoma, it is the second most common malignant bone sarcoma.
Manisha Chavan   +6 more
doaj   +1 more source

Ewing sarcoma with very late metastasis in the skull: a case report

open access: yesJournal of Medical Case Reports, 2022
Background Ewing sarcoma is a malignant bone tumor; however, its prognosis has improved since the development of modern chemotherapy. Although Ewing sarcoma outcomes have improved, issues related to late complications, secondary malignant neoplasms, and ...
Ryota Hagihara   +6 more
doaj   +1 more source

Variable expression of PIK3R3 and PTEN in Ewing Sarcoma impacts oncogenic phenotypes. [PDF]

open access: yesPLoS ONE, 2015
Ewing Sarcoma is an aggressive malignancy of bone and soft tissue affecting children and young adults. Ewing Sarcoma is driven by EWS/Ets fusion oncoproteins, which cause widespread alterations in gene expression in the cell.
Brian F Niemeyer   +5 more
doaj   +1 more source

Primary Ewing Sarcoma of Sphenoid Bone with Intracranial Extension: A Common Tumour at an Uncommon Location [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Primary Ewing Sarcoma of the cranial bone is rare, contributing to only 1% of all Ewing Sarcomas. Primary cranial Ewing Sarcoma occurs most commonly in temporal bone followed by parietal and occipital bones. Sphenoid bone is less commonly involved.
Guddi Rani Singh   +2 more
doaj   +1 more source

Ewing sarcoma of the pelvis: Clinical features and overall survival,

open access: yesCancer Treatment and Research Communications, 2022
Introduction: Primary Ewing Sarcoma of Bone is a malignancy whose treatment requires both systemic chemotherapy and local control through surgical resection and/or radiation. Ewing Sarcoma of the pelvis has been noted to confer a worse prognosis relative
Jeffrey Mark Brown   +4 more
doaj   +1 more source

18F-fluorodeoxyglucose positron emission tomography / computed tomography in primary Ewing sarcoma of the lung [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2022
Introduction. Ewing sarcoma is rare in medical practice, and evaluating positron emission tomography / computed tomography (PET/CT) imaging of soft tissue Ewing sarcoma is a challenge. Primary Ewing sarcoma of the lung is an infrequent diagnosis.
Zivgarević Ljiljana, Žunić Svetlana
doaj   +1 more source

Eltrombopag inhibits the proliferation of Ewing sarcoma cells via iron chelation and impaired DNA replication

open access: yesBMC Cancer, 2020
Background The treatment of Ewing sarcoma, an aggressive bone and soft tissue sarcoma, is associated with suboptimal outcomes and significant side-effects.
Torin Waters   +4 more
doaj   +1 more source

Repression of enhancer RNA PHLDA1 promotes tumorigenesis and progression of Ewing sarcoma via decreasing infiltrating T‐lymphocytes: A bioinformatic analysis

open access: yesFrontiers in Genetics, 2022
Background: The molecular mechanisms of EWS-FLI-mediating target genes and downstream pathways may provide a new way in the targeted therapy of Ewing sarcoma.
Runzhi Huang   +17 more
doaj   +1 more source

Irinotecan plus temozolomide in relapsed Ewing sarcoma: an integrated analysis of retrospective studies

open access: yesBMC Cancer, 2022
Highlights 1. Nearly 44% of relapsed Ewing sarcoma patients achieved an ORR after IT treatment. 2. Relapsed Ewing sarcoma treated with IT had an over 66% DCR. 3.
Bi-Cheng Wang, Bo-Ya Xiao, Guo-He Lin
doaj   +1 more source

Wolf in sheep's clothing: Primary orbital Ewing sarcoma in a child masquerading as internal angular dermoid

open access: yesOman Journal of Ophthalmology, 2022
Ewing sarcoma is one of the rare, highly malignant neuroectodermal tumors frequently involving bones. Primary orbital Ewing sarcoma is extremely uncommon.
Teena Mariet Mendonca   +5 more
doaj   +1 more source

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