Results 21 to 30 of about 19,643 (211)

Genome-wide functional perturbation of human microsatellite repeats using engineered zinc finger transcription factors

open access: yesCell Genomics, 2022
Summary: Repeat elements can be dysregulated at a genome-wide scale in human diseases. For example, in Ewing sarcoma, hundreds of inert GGAA repeats can be converted into active enhancers when bound by EWS-FLI1.
Y. Esther Tak   +16 more
doaj   +1 more source

SPOP and OTUD7A Control EWS–FLI1 Protein Stability to Govern Ewing Sarcoma Growth

open access: yesAdvanced Science, 2021
Chromosomal translocation results in development of an Ewing sarcoma breakpoint region 1‐Friend leukemia integration 1 (EWS–FLI1) fusion oncogene in the majority of Ewing sarcoma.
Siyuan Su   +13 more
doaj   +1 more source

Gastric Ewing Sarcoma identified on a Meckel's scan

open access: yesRadiology Case Reports, 2020
Ewing Sarcoma is a malignant small round blue cell tumor most commonly found in bones and soft tissues of the axial skeleton and extremities. The Ewing family of tumors, including peripheral neuroectodermal tumor, represent the second most common ...
Lavi Nissim, MD, Gerald Mandell, MD
doaj   +1 more source

Effect of Educational Guidelines on Mothers' Knowledge, Reported Practices, and Anxiety regarding their Children having Ewing Sarcoma [PDF]

open access: yesEgyptian Journal of Health Care
Background: Ewing tumors, also called Ewing sarcomas, are a class of malignancies that originate in the surrounding soft tissues or bones and have a few characteristics as common.
Heba Boshra Shehata   +5 more
doaj   +1 more source

Cutaneous Ewing Sarcoma and Ewing Sarcoma of the Bone: Distinct Diseases

open access: yesCase Reports in Oncology, 2018
Ewing sarcoma is an aggressive mesenchymal malignancy. It is the second most common bone tumor among children and adolescents and less commonly presents as a soft tissue or primary skin lesion.
Montreh Tavakkoli, Lisa Mueller
doaj   +1 more source

Congenital extraskeletal Ewing′s sarcoma of chest wall - A rare case report

open access: yesIndian Journal of Pathology and Microbiology, 2011
Congenital extraskeletal Ewing′s sarcoma or peripheral primitive neuroectodermal tumor is an extremely uncommon and invariably fatal tumor. We report a case of extraskeletal congenital Ewing′s sarcoma in a female fetus delivered at 34 weeks of gestation ...
Bhagyalakshmi Atla   +3 more
doaj   +1 more source

Ewing's Sarcoma [PDF]

open access: yesCA: A Cancer Journal for Clinicians, 1976
There are no known external causes of Ewing’ sarcoma, a form of bone cancer, although a small number of cases are linked to genetic abnormalities. This malignancy occurs with remarkable consistency in registry populations across Europe and the United States, including Los Angeles County. Few cases of it occur after age 30.
openaire   +3 more sources

Ewing's sarcoma of the calcaneum

open access: yesIndian Journal of Medical and Paediatric Oncology, 2017
Ewing's sarcoma of the calcaneum is rare. Radiological features of this tumor can be misinterpreted as other benign bone tumors due to its rarity. The overall prognosis of Ewing's sarcoma of calcaneum is inferior compared to other sites of this tumor.
Sherif, P Ajmal, Santa, A
openaire   +2 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Ewing′s sarcoma of the mandible

open access: yesNational Journal of Maxillofacial Surgery, 2011
Ewing's sarcoma is a malignant tumor of bones that primarily affects children and young adults. The true origin of this small round cell lesion still remains controversial. It was originally described by James Ewing in 1921 as arising from undifferentiated osseous mesenchymal cells; however, recent studies suggest that Ewing's tumor might be ...
Rao, B. H. Sripathi   +3 more
openaire   +3 more sources

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