Results 61 to 70 of about 82,773 (230)

Copine‐4 Paraneoplastic Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We characterize copine‐4 (CPNE4)‐IgG and report clinical associations. Among 844 samples with unclassified neural IgGs identified by mouse‐brain indirect immunofluorescence assay over 2 years, 5 samples (serum, 3; CSF, 2) from 3 patients produced a distinctive cerebrum‐restricted synaptic pattern.
Mimi S. Fang, Amy Ml Quek, Clement Yong, Amir Adeli, Gabrielle N. Conway, Connie E. Lesnick, Diana Anissian, Divyanshu Dubey, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael Gilligan, Andrew McKeon   +12 more
wiley   +1 more source

Primary mediastinal Ewing’s sarcoma presenting with sudden and severe chest pain: a case report

Frontiers in Oncology
Ewing’s sarcoma, characterized by small round cell morphology, is a rare malignancy, with mediastinal Ewing’s sarcoma being even less common. This case describes a distinctive presentation of primary mediastinal Ewing’s sarcoma in a 32-year-old male ...
Chen Su, Chen Su, Xiaobo Zhu, Xiaobo Zhu, Junjie Zhang, Junjie Zhang   +5 more
doaj   +1 more source

Latest developments in the pathobiology of Ewing sarcoma

Journal of Bone Oncology, 2022
Ewing's sarcoma (ES) is an aggressive malignant tumor commonly affecting adolescents. The standard of care includes surgical treatment and systemic therapies, although ES patients often develop drug resistance, leading to disease progression ...
Irina Karlina, Brett A. Schroeder, Kirill Kirgizov, Olga Romantsova, Andrey L. Istranov, Andrey Nedorubov, Peter Timashev, Ilya Ulasov   +7 more
doaj   +1 more source

A Living Multi‐Omics PDX Biobank of High‐Risk Sarcomas Reveals ecDNA‐Driven Oncogene Amplification in Osteosarcoma and Enables Preclinical Precision Oncology

Advanced Science, EarlyView.
A living multi‐omics sarcoma PDX biobank is enriched for high‐risk disease and preserves key patient tumor features at histopathological and molecular levels. Integrated profiling reveals ecDNA‐driven oncogene amplification in osteosarcoma and preferential retention of ecDNA during PDX evolution.
Weisong Zhao, Zhiwei Cheng, Kai Tian, Mengxiong Sun, Zhuoying Wang, Ming Jiao, Jens Luebeck, Kaiyuan Zhu, Xiao Zhang, Dongqing Zuo, Hongsheng Wang, Chongren Wang, Jiakang Shen, Xiaojun Ma, Gangyang Wang, Zongyi Wang, Jing Han, Kaiyuan Liu, Haoran Mu, Weiqi Ma, Yongyong Ren, Shibing Guo, Huangxin Tu, Lingfeng Yu, Yining Tao, Yu Lv, Hui Lu, Owen S. Chapman, Rishaan Kenkre, Lukas Chavez, Zhengdong Cai, Yuqin Yang, Wei Sun, Yafei Jiang, Yingqi Hua   +34 more
wiley   +1 more source

Primitive Neuroectodermal Tumor of the Cervix Uteri

International Journal of Hematology-Oncology and Stem Cell Research, 2012
Ewing’s sarcoma is a round cell malignancy of bone and soft tissue that occurs predominately in adolescents and young adults.It is an uncommon malignancy, but is recognized as the second most prevalent primary bone tumor worldwide.
Zineb Benbrahim, Christine Haie-Meder, Pierre Duvillard, Omar El Mesbahi, Axel Le Cesne, Patricia Pautier   +5 more
doaj  

A Dual‐Delivery System Designed to Overcome EV‐Mediated Ferroptosis Resistance for Efficient Solid Tumor Therapy

Advanced Science, EarlyView.
(A) Establishment and characterization of the osteosarcoma‐targeted dual‐delivery nanoplatform mBAP1/siENO1@LNP‐OTP for simultaneous regulation of BAP1 and ENO1 in tumor cells. (B) After intravenous administration, mBAP1/siENO1@LNP‐OTP preferentially accumulates at tumor sites through OTP‐mediated targeting.
Yechao Shen, Zhenguo Cao, Zenan Wang, Liang Chen, Jiahao Zhang, Linjie Zeng, Boren Tan, Hengyuan Li, Jiashan Lai, Jiangchu Lei, Fanglu Chen, Peng Lin, Zhenxuan Shao, Zhan Wang   +13 more
wiley   +1 more source

Primitive Neuroectodermal Tumor of the Cervix Uteri: A case report and review of literature

International Journal of Hematology-Oncology and Stem Cell Research, 2015
Ewing’s sarcoma is a round cell malignancy of bone and soft tissue that occurs predominately in adolescents and young adults.It is an uncommon malignancy, but is recognized as the second most prevalent primary bone tumor worldwide.
Zineb Benbrahim, Christine Haie-Meder, Pierre Duvillard, Omar El-Mesbahi, Axel Le-Cesne, Patricia Pautier   +5 more
doaj  

Imaging Responses in Ewing's sarcoma patient 2.

, 2013
FDG PET /CT in patient 2 with Ewing's sarcoma response to IMCA12+Temsirolimus combination and then emergence of resistance. Left panel shows pre-treatment FDG PET/CT scan of the thorax showing metastatic Ewing's sarcoma in the lung.
Razelle Kurzrock (160706), Pete Anderson (353753), Vivek Subbiah (353745), Robert E. Brown (353747), Aung Naing (160702), Helen Chen (105332), Laurence Doyle (353748), Robert Benjamin (353751), Patricia LoRusso (353749)   +8 more
core   +1 more source

Nanofabricated Biomaterials Model Tumor Extracellular Matrix Topography

Advanced NanoBiomed Research, EarlyView.
The unique structure and composition of the tumor microenvironment and its associated extracellular matrix (ECM) exert profound effects on cancer cell behavior that are difficult to model in vitro. This perspective discusses the utility of nanofabricated biosubstrates, such as the novel collagen‐coated nanogrooved array, for recapitulating the ...
Vic Zamloot, JinSeok Park
wiley   +1 more source

Ewing's Sarcoma Of The Head And Neck. [PDF]

, 2015
CONTEXT: Ewing's sarcoma is a rare neoplasm, which usually arises in long bones of the limbs and in flat bones of the pelvis, with the involvement of head and neck bones being very unusual. CASE REPORT: a case of Ewing's sarcoma occurring in the mandible
Fonseca A.S., Crespo A.N., Bortoleto Jr. A.E., Paschoal J.R., Mezzalira R.   +4 more
core