Results 51 to 60 of about 6,148 (193)

Ewing's Sarcoma Omental Odyssey: Unraveling Rare Metastasis and Unforeseen Treatment Outcome on FDG PET/CT: Case Report with Review of Literature

Indian Journal of Medical and Paediatric Oncology
Ewing's sarcoma is an uncommon and highly metastatic form of sarcoma affecting children and young adults, occurring in approximately 1 in 1.5 million individuals, with a predominance in males.
Prakash Singh, Yogita Khandelwal, Manish Ora, Shivam Singh   +3 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Adult-onset primary Ewing’s sarcoma of the right atrium: a case report

Surgical Case Reports, 2019
Background Primary cardiac tumors, which are only detected in 0.001–0.03% of autopsies, are rare. Only 25% of primary cardiac tumors are malignant, of which 95% are sarcomas.
Jun Ushigusa, Yosuke Mukae, Masanori Takamatsu, Eijiro Nogami, Akira Furutachi, Manabu Itoh, Junji Yunoki, Takahiro Nishida   +7 more
doaj   +1 more source

Pediatric Patient with a Diagnosis of Pelvic Extraosseous Ewing’s Sarcoma: A Case Report

Journal of the Belgian Society of Radiology, 2023
Ewing’s sarcoma (ES) is a malignant tumor that arises mainly from bone tissue. Primary extraosseous Ewing sarcoma (EES) is a rare form of the Ewing’s sarcoma family of tumor, and pelvic localization is even more unusual, considered to be one of the ...
Sabrina Amaouche, Christine Devalck, Nasroolla Damry   +2 more
doaj   +1 more source

Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution

Advanced Science, EarlyView.
This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida, Yanghao Zhong, Akiko Kumagai, William G. Dunphy, Shasha Chong   +4 more
wiley   +1 more source

Primary vaginal Ewing’s sarcoma/primitive neuroectodermal tumour: diagnostic and treatment challenges [PDF]

Journal of Clinical and Scientific Research, 2014
Extra osseous Ewing’s sarcoma/primitive neuroectodermal tumour (PNET) of the genital tract of women is scarcely described in the literature and involvement of the vagina is even rarer with a very few cases reported so far.
Pranabandhu Das, K. Gunaseelan, Debdatta Basu, Ramesh Ananthakrishnan, K.S Reddy   +4 more
doaj   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Primary Cervical Extraosseous Ewing’s Sarcoma Originated from the Sternocleidomastoid Muscle: A Case Report and Review of the Literature

Case Reports in Otolaryngology
Extraosseous Ewing’s sarcoma is extremely rare in the soft tissues of the neck, especially in the sternocleidomastoid muscle. It usually manifests clinically as a rapidly growing mass that shows great potential for local spread.
Sasa Jakovljevic, Nenad Arsovic, Zoran Dudvarski, Nemanja Radivojevic, Katarina Jovanovic, Neda Mladenovic, Snezana Babac   +6 more
doaj   +1 more source

UGT1A1 genotype testing for irinotecan: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Abstract Irinotecan, a topoisomerase I inhibitor, is available as both non‐pegylated and pegylated formulations. The non‐pegylated formulation is licensed for use in advanced colorectal cancer either in combination with other agents or as monotherapy.
Dharmisha Chauhan, Cinzia Dello Russo, Jack Thompson, Dyfrig A. Hughes, Katherine Payne, Maria Tsakiroglou, Paul Ross, Rena Chauhan, Simon Jenkinson, Jessica Keen, Sophie Harding, Eleanor Lau, Michael Braun, Roshan Agarwal, Richard Adams, Elisabeth Rolf, Farah Al‐Sheikhli, Sarah Mitchell, Ruth Hammond, Rosie Roberts, Lorna Cairns, Shirley Heggarty, Janet Graham, Justin Mencel, Munir Pirmohamed   +24 more
wiley   +1 more source

Role of fluoroethyl tyrosine positron emission tomography-computed tomography scan in differentiating ewing's sarcoma from osteomyelitis

World Journal of Nuclear Medicine, 2019
Ewing's sarcoma is a kind of undifferentiated reticulocytic sarcoma, which was first reported in 1921 by James Ewing. It is difficult to differentiate Ewing's sarcoma from osteomyelitis on computed tomography (CT) and X-ray and hence cytological ...
Hitesh Aggarwal, Maria D'souza, Puja Panwar, Neeru Jyotsna, Tauheed Alvi, Yachna Solanki, Tarakant Kumar, Rajnish Sharma   +7 more
doaj   +1 more source