Results 41 to 50 of about 5,957 (165)

Silent Malignant Occipital Swelling

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2018
Ewing's sarcoma commonly reported in long bones and pelvis. Primary Ewing's sarcoma of the cranium is rare. They behave differently from their counterpart involving the long bones. They usually respond well to chemotherapy and radiotherapy.
Sumeet V Sasane, Sushanta K Sahoo, Chhitij Srivastava, Ajay Singh, Bal Krishna Ojha   +4 more
doaj   +1 more source

Identification of Common Oncogenic Genes and Pathways Both in Osteosarcoma and Ewing’s Sarcoma Using Bioinformatics Analysis

Journal of Immunology Research, 2022
This study was aimed at exploring common oncogenic genes and pathways both in osteosarcoma and Ewing’s sarcoma. Microarray data were obtained from the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) were identified using the
Jingwei Zhang, Junchao Huang, Wenjun Liu, Liang Ding, Dongdong Cheng, Haijun Xiao   +5 more
doaj   +1 more source

Ewing′s sarcoma of the mandible

National Journal of Maxillofacial Surgery, 2011
Ewing's sarcoma is a malignant tumor of bones that primarily affects children and young adults. The true origin of this small round cell lesion still remains controversial. It was originally described by James Ewing in 1921 as arising from undifferentiated osseous mesenchymal cells; however, recent studies suggest that Ewing's tumor might be ...
Rao, B. H. Sripathi, Rai, Gunachander, Hassan, Shahid, Nadaf, Afreen   +3 more
openaire   +3 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Peripheral primitive neuroendocrine tumor of the chest wall—A case report with pathological correlation

Radiology Case Reports, 2018
Primitive neuroectodermal tumor is a high-grade malignant tumor originating from the neural crest and neuroectoderm, which can be subdivided into central and peripheral categories.
Jidi Gao, MD, Erika Chow, BA, Aishatu Aloma, MD, Payal Gupta, MD   +3 more
doaj   +1 more source

Primary Ewing’s Sarcoma of the Spine: About a Case

Global Pediatric Health, 2022
Ewing’s sarcoma is a primary malignant bone tumor affecting individuals in the second decade of life. Primary sarcomas of the spine are rare and the occurrence of primary Ewing’s sarcoma in the spine is very rare.
Amine Cherraqi MD, Abir Lemrabet MD, Ibrahima Diallo Dokal MD, Najlae Lrhorfi MD, Hicham Belghiti MD, Nazik Allali PhD, Latifa Chat PhD   +6 more
doaj   +1 more source

Ewing′s sarcoma of zygoma

Journal of Oral and Maxillofacial Pathology, 2009
Ewing's sarcoma is a malignant, small, round cell neoplasm that normally affects the long bones of the limbs or the pelvis. It is a relatively frequent malignant bone tumor in children. The occurrence of the primary tumor in the facial region is approximately 2%, with most of the cases affecting the mandible.
Deshingkar, SA, Barpande, SR, Tupkari, JV   +2 more
openaire   +3 more sources

Harnessing MDM2‐Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma

Advanced Science, EarlyView.
MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou, Xian Guan, Nan Li, Ying Zhang, Long Xie, Xingze Huang, Zhipeng Zhu, Zhuolin Ren, Xiaoyan Yu, Hanjun Guo, Yuanfang Wu, Lin Ma, Suya Zheng, Jingyao Zhang, Jiyang Liu, Victor Kuanmin Lee, Wenhao Chen, H. Phillip Koeffler, Jinhu Wang, Xin Han, Ye Chen, Liang Xu   +21 more
wiley   +1 more source

Ewing’s Sarcoma of the Breast in a Young Woman: A Case Report and Review of the Literature

Frontiers in Oncology, 2022
Ewing’s Sarcoma Family Tumors (ESFT) include classic Ewing’s sarcoma of bone, extra-skeletal Ewing’s sarcoma (EES), malignant small cell tumor of the chest wall (Askin tumor), and soft tissue-based Peripheral Primitive Neuroectodermal tumors (pPNET). The
Simona Papi, Francesca Combi, Francesca Combi, Silvia Segattini, Silvia Accogli, Enza Palma, Anna Gambini, Alessia Andreotti, Gabriele Luppi, Giovanni Tazzioli   +9 more
doaj   +1 more source

A Non‐Canonical Core Transcriptional Regulatory Circuit Orchestrates Chromatin Reprogramming to Drive Osimertinib Resistance in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
A non‐canonical core transcriptional regulatory circuit, composed of ID3, SMAD3, and NR2F2, drives Osimertinib resistance in non‐small cell lung cancer through super‐enhancer‐mediated activation of EPAS1, which couples neuroendocrine differentiation with ferroptosis evasion.
Aochu Liu, Zhenguo Liu, Lizhen Jiang, Andong Huang, Xinqing Lin, Xinyue Li, Bingyuan Liu, Shiwen Hu, Qiang Pan, Junjun Huang, Liyuan Yin, Liling Jiang, Wei Yi, Wenjun Mao, Yueyuan Zheng, Xianping Shi   +15 more
wiley   +1 more source