Results 91 to 100 of about 244,614 (241)

Ewing’s sarcoma in maxilla

BMJ Case Reports, 2019
Ewing sarcoma is a lesion of bone, described in small round cell neoplasm. This tumour resembles primitive neuroectodermal tumour both clinically and histologically. Major difference between these two is that the former arises in the bone and the later in soft tissue.
Madhusudan, Astekar, Shipra, Saxena, Aditi, Murari, Bhari Sharanesha, Manjunatha   +3 more
openaire   +3 more sources

A guide to transcriptional cyclin‐dependent kinases in cancer

The FEBS Journal, EarlyView.
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin, Salla Kyheröinen, Ricky W. Johnstone   +2 more
wiley   +1 more source

Ethnicity and age disparties in ewing sarcoma outcome

, 2012
Ethnicity and age disparties in ewing sarcoma ...
KOOHBANANI B, RUGGIERI, PIETRO, HAN G, BUI M. M., REED D, YI D, HENDERSON E   +6 more
core   +1 more source

Salient Features of Mesenchymal Stem Cells – Implications for Ewing Sarcoma Modeling

Frontiers in Oncology, 2013
Despite a heightened appreciation of the many defining molecular aberrations in Ewing sarcoma, the cooperative genetic environment and permissive cell of origin essential for EWS/ETS-mediated oncogenesis remain elusive. Consequently, inducible animal and
Michael James Monument, Nicholas eBernthal, R. Lor eRandall   +2 more
doaj   +1 more source

Ewing's sarcoma [PDF]

Cancer, 1952
L J, McCORMACK, M B, DOCKERTY, R K, GHORMLEY   +2 more
openaire   +2 more sources

Supplementary Figure S5 from Ewing Sarcoma Single-cell Transcriptome Analysis Reveals Functionally Impaired Antigen-presenting Cells

, 2023
Immune cell landscape of Ewing ...
Hans Clevers (17276043), Thanasis Margaritis (17276034), Margit Bleijs (17276031), Frank C. P. Holstege (17276040), Marc van de Wetering (17276037), Lindy L. Visser (15011166)   +5 more
core   +1 more source

Merkel cell carcinoma: an updated guide for pathologists

Histopathology, EarlyView.
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley   +1 more source

Combined inhibition of CDK4/6 and PI3K pathways exhibit highly synergistic activity and translational potential in Ewing sarcoma

Translational Oncology
Ewing sarcoma is a highly aggressive solid malignancy affecting children and young adults. Ewing sarcoma is driven primarily by EWSR1::FLI1, a fusion oncoprotein that has been notoriously difficult to target with traditional pharmacologic agents.
Helen F. Gloege, Maria Ana Isabel C. De Los Santos, Advaita Chakraborty, Madhav Chadha, Alejandra Aguilar-Quintero, Min Shen, Caleb O. Heaslip, Sarah Finstuen-Magro, Brigit McDannell, Mohammad Tanhaemami, Stephanie Meyer, Kelly Klega, Ya-Qin Zhang, David S. Shulman, Steven G. DuBois, Matthew D. Hall, Anne-Florence Blandin, Brian D. Crompton   +17 more
doaj   +1 more source

Primary Ewing sarcoma of the kidney: a symptomatic presentation and review of the literature

Therapeutic Advances in Urology, 2013
The objective of this review is to discuss the unique nature of primary renal Ewing sarcoma, including incidence, presentation and management. We also report on a common pattern of presentation, consisting of acute flank pain mimicking a renal stone ...
Tariq S. Hakky, Americo A. Gonzalvo, Jorge L. Lockhart, Alejandro R. Rodriguez   +3 more
doaj   +1 more source

EWS–FLI1 Retargets BAF Chromatin Remodeling Complexes in Ewing Sarcoma

, 2017
BAF recruitment to GGAA microsatellites activates the Ewing sarcoma transcriptional program.

core   +1 more source