Results 51 to 60 of about 44,634 (268)

The effect of Imp-2 on Ewing sarcoma cancer stem cells: when epigenetics orchestrate tumor growth [PDF]

, 2015
Ewing's sarcoma family tumors Ewing sarcoma is part of the Ewing's sarcoma family tumors (ESFTs) that includes peripheral primitive neuroectodermal tumor (PNET), extraosseous ewing sarcoma, Askin's tumor and atypical Ewing sarcoma.
BAKARIC, A.
core  

The epidemiology of bone cancer in 0 - 39 year olds in northern England, 1981 - 2002 [PDF]

, 2010
Background: There is a paucity of recent epidemiological data on bone cancers. The aim of this study was to describe incidence and survival patterns for bone cancers diagnosed during 1981 - 2002.Methods: Cases aged 0 - 39 years (236 osteosarcomas, 166 ...
Rachel Eyre, Richard G Feltbower, Peter W James, Karen Blakey, Emmanuel Mubwandarikwa, David Forman, Patricia A McKinney, Mark S Pearce, Richard JQ McNally   +8 more
core   +1 more source

The Macrophage Inhibitor CNI-1493 Blocks Metastasis in a Mouse Model of Ewing Sarcoma through Inhibition of Extravasation.

PLoS ONE, 2015
Metastatic Ewing Sarcoma carries a poor prognosis, and novel therapeutics to prevent and treat metastatic disease are greatly needed. Recent evidence demonstrates that tumor-associated macrophages in Ewing Sarcoma are associated with more advanced ...
Anthony J Hesketh, Caroline Maloney, Christopher A Behr, Morris C Edelman, Richard D Glick, Yousef Al-Abed, Marc Symons, Samuel Z Soffer, Bettie M Steinberg   +8 more
doaj   +1 more source

The combination of temozolomide-irinotecan regresses a doxorubicin-resistant patient-derived orthotopic xenograft (PDOX) nude-mouse model of recurrent Ewing's sarcoma with a FUS-ERG fusion and CDKN2A deletion: Direction for third-line patient therapy. [PDF]

, 2017
The aim of the present study was to determine the usefulness of a patient-derived orthotopic xenograft (PDOX) nude-mouse model of a doxorubicin-resistant metastatic Ewing's sarcoma, with a unique combination of a FUS-ERG fusion and CDKN2A deletion, to ...
Bouvet, Michael, Chishima, Takashi, Dry, Sarah M, Eckardt, Mark A, Eilber, Fritz C, Elliott, Irmina A, Endo, Itaru, Hiroshima, Yukihiko, Hoffman, Robert M, Igarashi, Kentaro, Kawaguchi, Kei, Kiyuna, Tasuku, Li, Yunfeng, Matsuyama, Ryusei, Miyake, Kentaro, Miyake, Masuyo, Momiyama, Masashi, Murakami, Takashi, Nelson, Scott D, Russell, Tara A, Singh, Arun S   +20 more
core   +1 more source

Ewing`S Sarcoma

Journal of Education, Health and Sport, 2017
Budny Agnieszka, Litak Jakub, Kulesza Bartłomiej, Czyżewski Wojciech, Grochowski Cezary. Ewing`s Sarcoma. Journal of Education, Health and Sport. 2017;7(6):265-272. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.804631 http://ojs.ukw.edu.pl/index.php/johs/article/view/4534 The journal has had 7 points in Ministry of Science and ...
Agnieszka Budny, Jakub Litak, Bartłomiej Kulesza, Wojciech Czyżewski, Cezary Grochowski   +4 more
openaire   +3 more sources

Renal Ewing sarcoma with extensive neuroectodermal differentiation: Case report and literature review

Acta Marisiensis - Seria Medica, 2023
Ewing sarcoma with renal localization is one of the rarest members of the Ewing sarcoma family with less than 200 cases reported in the Medline database.
Sava Alexandra Daniela, Szekely Tiberiu Bogdan, Togănel Cornelia, Vacar Adela, Bungardean Catalina, Gurzu Simona   +5 more
doaj   +1 more source

K-Ras and p53 mouse model with molecular characteristics of human rhabdomyosarcoma and translational applications

Disease Models & Mechanisms, 2022
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children, with overall long-term survival rates of ∼65-70%. Thus, additional molecular insights and representative models are critical for identifying and evaluating new treatment ...
Kengo Nakahata, Brian W. Simons, Enrico Pozzo, Ryan Shuck, Lyazat Kurenbekova, Zachary Prudowsky, Kshiti Dholakia, Cristian Coarfa, Tajhal D. Patel, Lawrence A. Donehower, Jason T. Yustein   +10 more
doaj   +1 more source

Vascular Reconstruction in Extremity Soft Tissue Sarcomas: A Systematic Review and Single‐Arm Meta‐Analysis

Journal of Surgical Oncology, EarlyView.
ABSTRACT Introduction The management of extremity soft tissue sarcomas (STS) involving major vessels presents unique challenges, historically leading to amputation. Advances in vascular reconstruction have enabled limb‐sparing surgery (LSS), but outcomes and perioperative risks remain uncertain.
Lucas Monteiro Delgado, Bernardo Fontel Pompeu, Vinícius dos Santos Macedo, Gabriel Henrique Acedo Martins, Eric Pasqualotto, Matheus Reginato Araujo, Julia Hoici Brunini, Victor Andrade Nunes, Cláudia Theis, Samuel Aguiar Junior   +9 more
wiley   +1 more source

The second European interdisciplinary Ewing sarcoma research summit – A joint effort to deconstructing the multiple layers of a complex disease [PDF]

, 2016
Despite multimodal treatment, long term outcome for patients with Ewing sarcoma is still poor. The second “European interdisciplinary Ewing sarcoma research summit” assembled a large group of scientific experts in the field to discuss their latest ...
Amatruda, James, Brunet, Erika, Burdach, Stefan, Cidre-Aranaz, Florencia, Kovar, Heinrich, Álava Casado, Enrique de   +5 more
core  

BCL11B is up-regulated by EWS/FLI and contributes to the transformed phenotype in Ewing sarcoma.

PLoS ONE, 2013
The EWS/FLI translocation product is the causative oncogene in Ewing sarcoma and acts as an aberrant transcription factor. EWS/FLI dysregulates gene expression during tumorigenesis by abnormally activating or repressing genes.
Elizabeth T Wiles, Bianca Lui-Sargent, Russell Bell, Stephen L Lessnick   +3 more
doaj   +1 more source