Results 61 to 70 of about 244,614 (241)
Superficial Ewing Sarcoma of the Rectum: A Case Report and the Utility of Molecular Diagnostics. [PDF]
J Cutan PatholABSTRACT Ewing sarcoma is an undifferentiated small round cell sarcoma that most commonly presents as a malignant bone tumor in pediatric and young adult patients. The diagnosis is typically confirmed by molecular genetic identification of a fusion protein, most commonly involving members of the FET and ETS gene families.
Muldoon JL +3 more
europepmc +2 more sources
Diagnostic Cytopathology, EarlyView.ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley +1 more source
Recent advances in targeted therapy for Ewing sarcoma [version 1; referees: 2 approved]
F1000Research, 2016 Ewing sarcoma is an aggressive, poorly differentiated neoplasm of solid bone that disproportionally afflicts the young. Despite intensive multi-modal therapy and valiant efforts, 70% of patients with relapsed and metastatic Ewing sarcoma will succumb to ...
Kathleen I. Pishas, Stephen L. Lessnick
doaj +1 more source
Diagnostic Cytopathology, EarlyView.ABSTRACT Background Primary pulmonary mesenchymal neoplasms with EWSR1::CREM fusion are rare. These lesions are challenging to diagnose by morphology and immunohistochemistry alone. Case A 66‐year‐old woman (ex‐smoker) was found to have a 1.3‐cm right lower lobe lung nodule that had grown very slowly over a 9‐year period.
Priya Upadhyay +2 more
wiley +1 more source
Fine needle aspiration cytology diagnosis of paravertebral extraosseus Ewing′s sarcoma
Journal of Cytology, 2010 Extraskeletal Ewing′s sarcoma (EES) is a rare tumor. Paravertebral Ewing′s sarcoma requires more extensive therapy as compared to Ewing′s sarcoma of bone.
Buch Archana +4 more
doaj
Immuno-stimulation by OX40 ligand transgenic Ewing sarcoma cells
Frontiers in Oncology, 2015 Interleukin-2 (IL-2) transgenic Ewing sarcoma cells can induce tumor specific T and NK cell responses and reduce tumor growth in vivo and in vitro. Nevertheless, the efficiency of this stimulation is not high enough to inhibit tumor growth completely. In
Dajana eReuter +3 more
doaj +1 more source
Deciphering transcriptome complexity via long‐read sequencing
iMeta, EarlyView.Long‐read sequencing is transforming transcriptomics from gene‐level quantification to isoform‐resolved interpretation by directly resolving full‐length transcript structures, transcription in repetitive regions, and linked molecular features. This review provides an end‐to‐end roadmap covering sequencing platforms, library preparation strategies ...
Chuwen Xu +21 more
wiley +1 more source
EWS/FLI1 target genes and therapeutic opportunities in Ewing sarcoma
Frontiers in Oncology, 2015 Ewing sarcoma family of tumors are aggressive bone malignancies that affect children and young adults. Ewing sarcoma is the second most common primary bone malignancy in pediatric patients.
Florencia eCidre, Javier eAlonso
doaj +1 more source
Journal of Surgical Oncology, EarlyView.ABSTRACT Introduction Sarcomas are rare malignancies that affect both adults and children. Surgical removal with negative histopathological margins is the foundation of sarcoma treatment. Failure to achieve negative margins puts patients at risk of local recurrence (LR). LR rates range between 10% and 30%.
Sumail Bhogal +13 more
wiley +1 more source
Acta Marisiensis - Seria Medica, 2023 Ewing sarcoma with renal localization is one of the rarest members of the Ewing sarcoma family with less than 200 cases reported in the Medline database.
Sava Alexandra Daniela +5 more
doaj +1 more source