Results 51 to 60 of about 19,217 (182)
Recent advances in targeted therapy for Ewing sarcoma [version 1; referees: 2 approved]
Ewing sarcoma is an aggressive, poorly differentiated neoplasm of solid bone that disproportionally afflicts the young. Despite intensive multi-modal therapy and valiant efforts, 70% of patients with relapsed and metastatic Ewing sarcoma will succumb to ...
Kathleen I. Pishas, Stephen L. Lessnick
doaj +1 more source
ABSTRACT Background Primary pulmonary mesenchymal neoplasms with EWSR1::CREM fusion are rare. These lesions are challenging to diagnose by morphology and immunohistochemistry alone. Case A 66‐year‐old woman (ex‐smoker) was found to have a 1.3‐cm right lower lobe lung nodule that had grown very slowly over a 9‐year period.
Priya Upadhyay +2 more
wiley +1 more source
Deceptive Thyroid Pathologies: Anaplastic Thyroid Carcinoma Mimics and Clinical Implications
ABSTRACT Background Beyond follicular‐derived thyroid carcinomas, lymphomas, and metastatic disease, there are rare pathologies of the thyroid gland that represent a challenge. We report patients with unusual malignancies that mimic similar aggressive cancers. Methods Retrospective case series.
David Z. Allen +12 more
wiley +1 more source
Characteristics of human Ewing/PNET sarcoma models
Ewing/PNET (peripheral neuroepithelioma) tumors are rare aggressive bone sarcomas occurring in young people. Rare-disease clinical trials can require global collaborations and many years. In vivo models that as accurately as possible reflect the clinical
Teicher Beverly +5 more
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Immuno-stimulation by OX40 ligand transgenic Ewing sarcoma cells
Interleukin-2 (IL-2) transgenic Ewing sarcoma cells can induce tumor specific T and NK cell responses and reduce tumor growth in vivo and in vitro. Nevertheless, the efficiency of this stimulation is not high enough to inhibit tumor growth completely. In
Dajana eReuter +3 more
doaj +1 more source
Ewing sarcoma with renal localization is one of the rarest members of the Ewing sarcoma family with less than 200 cases reported in the Medline database.
Sava Alexandra Daniela +5 more
doaj +1 more source
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children, with overall long-term survival rates of ∼65-70%. Thus, additional molecular insights and representative models are critical for identifying and evaluating new treatment ...
Kengo Nakahata +10 more
doaj +1 more source
ABSTRACT Background Salivary gland carcinomas are uncommon malignancies with various histological subtypes harboring fusion genes. The EWSR1::ATF1 fusion gene, resulting from a translocation between chromosomes 12 and 22, is frequently observed in hyalinizing clear cell carcinoma (HCCC). However, the role of this fusion gene in HCCC oncogenesis remains
Yuri Hirai +13 more
wiley +1 more source
Ewing's sarcoma of the hand [PDF]
A 54-year-old woman presented with a 12-month history of pain and a firm fixed mass on the dorsum of the right hand (figure 1). Physical examination revealed a firm circumferential swelling of the hand. The laboratory findings were within normal limits. Figure 1 Clinical view showing swelling of the right hand.
Khaled, Bouzaidi +3 more
openaire +2 more sources
Fine needle aspiration cytology diagnosis of paravertebral extraosseus Ewing′s sarcoma
Extraskeletal Ewing′s sarcoma (EES) is a rare tumor. Paravertebral Ewing′s sarcoma requires more extensive therapy as compared to Ewing′s sarcoma of bone.
Buch Archana +4 more
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