Results 31 to 40 of about 11,588,804 (234)

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Tracking error: ex-ante versus ex-post measures [PDF]

open access: yes, 2001
In this paper we show that ex-ante and ex-post tracking errors must necessarily differ, since portfolio weights are ex-post stochastic in nature. In particular, ex-post tracking error is always larger than ex-ante tracking error.
Satchell, S. (Stephen), Hwang, Soosung
core  

Individual Response Variation in the Effects of Weight Loss and Exercise on Insulin Sensitivity and Cardiometabolic Risk in Older Adults

open access: yesFrontiers in Endocrinology, 2020
Weight loss induced by decreased energy intake (diet) or exercise generally has favorable effects on insulin sensitivity and cardiometabolic risk. The variation in these responses to diet-induced weight loss with or without exercise, particularly in ...
Andrea M. Brennan   +5 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Archeologische begeleiding plangebied Poeldonk te Den Dungen, Gemeente Sint-Michielsgestel

open access: yes, 2021
In 2018 en 2019 heeft Ex-Situ Archeologie een archeologische begeleiding uitgevoerd volgens het protocol proefsleuven en/of opgraving in het plangebied Poeldonk te Den Dungen in de gemeente Sint- Michielsgestel.
Hoegen, drs R.D. (Ex-Situ Archeologie B.V.)
core   +1 more source

Oil Price Flux and Macroeconomy of Oil Exporters

open access: yesJournal of Accounting and Finance in Emerging Economies, 2020
Oil is an important energy source, embodies the largest commodity market in the world. Global economic performance has been highly correlated with oil price changes.
Madiha Riaz   +3 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Planning the integration of ex situ plant conservation in Tasmania [PDF]

open access: yes, 2013
Tasmania has a strong record of successful in situ plant conservation but there will always be a role for the integration of various ex situ measures into a plant conservation program due to pressure by threatening processes on wild populations.
Crane, Nepelle   +2 more
core  

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