Results 41 to 50 of about 681,327 (243)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Analysis of fluctuations in ex-core neutron detector signal in Krško NPP during an earthquake
Nuclear Engineering and TechnologyDuring an earthquake on December 29th 2020, the Krško NPP automatically shutdown due to the trigger of the negative neutron flux rate signal on the power range nuclear instrumentation. From the time course of the detector signal, it can be concluded that
Tanja Goričanec +3 more
doaj +1 more source
Confidence and unemployment in the European Union: a lesson from the 2004 enlargement
Notas Económicas, 2007 We use data for the monthly unemployment rate and consumer confidence indicator in the European Union to study whether there is a relationship between unemployment and confidence.
António Caleiro
doaj +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Effects of side walls on facade flame entrainment and flame height from opening in compartment fires
MATEC Web of Conferences, 2013 This paper presents an investigation of the side wall effects on facade flames ejected from the opening (such as a window) of an under-ventilated room fire.
Hu L.H. +4 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Artery Research, 2016 Objectives: Hemodialysis patients are at greater risk of increased arterial stiffness. Regular aerobic exercise has been shown to reduce arterial stiffness in hemodialysis patients.
Alexandra B. Cooke +4 more
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Change-point analysis for population scaled recombination rate along the Z chromosome.
, 2023 Change-point analysis for population scaled recombination rate along the Z chromosome.
Bengt Hansson (41898) +7 more
core +1 more source