Results 121 to 130 of about 173,037 (298)

Quantitative Mass Spectrometry‐Based Biodistribution of Monoclonal Antibodies: An Alternative to Radio‐Biodistribution

Advanced Science, EarlyView.
Monoclonal antibodies are powerful anticancer therapeutics targeting tumor‐associated antigens. Mass spectrometry enables precise and accurate quantification of mAbs in tumor plasma and healthy organs. Unlike ligand binding assay and radioactivity, mass spectrometry does not suffer from matrix effects and labelling artefacts while facilitating method ...
Domenico Ravazza, Sheila Dakhel Plaza, Samuele Cazzamalli, Andrea Ciamarone, Andrea Galbiati, Riccardo Stucchi, Frederik Peissert, Emanuele Puca, Dario Neri, Ettore Gilardoni   +9 more
wiley   +1 more source

Coping with ex ante Regulations and ex post Liability Rules for Planting Bt-maize – The Portuguese Experience

This study investigates the attitude and practices of GM and non-GM maize farmers in Portugal. Thirty seven GM maize farmers were interviewed representing 22.5% of the total number of GM maize notifications in the country.
Fevereiro, P., Skevas, Theodoros, Wesseler, Justus   +2 more
core  

Internet Advertising and the Generalized Second Price Auction: Selling Billions of Dollars Worth of Keywords [PDF]

We investigate the "generalized second price" auction (GSP), a new mechanism which is used by search engines to sell online advertising that most Internet users encounter daily. GSP is tailored to its unique environment, and neither the mechanism nor the
Michael Ostrovsky, Michael Schwarz, Benjamin Edelman   +2 more
core  

Enterprise resource planning system implementation and success measurement : case study of a small to medium sized enterprise [PDF]

, 2014
It is widely believed that major financial benefits can be achieved by organisations implementing Enterprise Resource Planning software. It is also believed that such systems are a time consuming and a costly endeavour which can result in loss of ...
Shaikh, N.
core  

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Developing a methodology for the ex-post assessment of Building Energy Efficiency Special Planning in Beijing during the 12th Five-Year Plan" period

, 2019
In order to carry out an ex-post assessment of the completed Building Energy Efficiency Special Planning, a comprehensive ex-post assessment methodology is established. The methodology sets out the ex-post assessment criteria from three dimensions and 27
Wang, Binyu, Liu, Yuming, Xu, Minghui, Liu, Tingting   +3 more
core   +1 more source

Implementation of Early Childhood Education Kits in Higher Education Student Learning: Ex-post Facto Study of Open University Students

JPUD - Jurnal Pendidikan Usia Dini
The ECE kit is practical and has benefits in the lecture process for The Open University ECE Bachelor's study program, which aims to produce professional ECE teachers who can work globally. This research aims to see the results of implementing the ECE kit 2023 from the perspective of students as ECE kit users. This research is an ex-post facto research
Nur Widhi, Ernayanti, Amini, Mukti
openaire   +2 more sources

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Post-War Peacebuilding Reviewed: A Critical Exploration of Generic Approaches to Post-War Reconstruction

, 2005
YesPeacebuilding, as a remedy for all the ailments afflicting any society emerging from war, has placed this complex and overloaded concept at the centre of a growing network of actors engaged in its formulation and implementation.
Llamazares, Monica
core  

Atomic Defects in Layered Transition Metal Dichalcogenides for Sustainable Energy Storage and the Intelligent Trends in Data Analytics

Advanced Science, EarlyView.
This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo, Ying Yang, Zizhen Fu, Fengqi Liu, Susu Fang, Kele Xu, Shanshan Wang   +6 more
wiley   +1 more source