Results 141 to 150 of about 173,037 (298)

Scalable Mechanism Design for the Procurement of Services with Uncertain Durations

, 2010
In this paper, we study a service procurement problem with uncertainty as to whether service providers are capable of completing a given task within a specified deadline. This type of setting is often encountered in large and dynamic multi-agent systems,
Larson, Kate, Stein, Sebastian, Jennings, Nicholas R., Jennings, Nicholas R, Gerding, Enrico, Rogers, Alex   +5 more
core  

INDAGINI DIAGNOSTICHE INTEGRATE EX POST PER IL MONITORAGGIO DI INTERVENTI DI RESTAURO ARCHITETTONICO

Archeomatica, 2012
La diagnostica strumentale in situ ha acquistato, da circa un ventennio, un ruolo determinante nella fase di defi nizione progettuale del restauro architettonico soprattutto conservativo; molto meno diffusa è invece la pratica della sua applicazione in ...
Vittorio Ceradini, Alessia Bianco
doaj  

Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity Testing

Advanced Science, EarlyView.
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng, Cinzia Esposito, Andrej Benjak, Matthias S. Matter, Miriam Cieri, Camilla De Carlo, Philipp Sedlaczek, Fabian Haak, Mattia Marinucci, Gabriel Fridolin Hess, Otto Kollmar, Mairene Coto‐Llerena, Luca Di Tommaso, Visar Vela, Lukas Bubendorf, Luigi M. Terracciano, Charlotte K. Y. Ng, Salvatore Piscuoglio   +17 more
wiley   +1 more source

Effects of the implementation of matrix support in the operation of the community mental health network in a medium-sized Brazilian municipality: an ex-ante and ex-post evaluation

Abstract Background The implementation of shared care strategies has been a global response to the challenge of the mental health care gap at primary levels of care and the lack of integration of health networks. In the Brazilian context, this perspective takes shape through Matrix Support, an interdisciplinary collaboration proposal that aims
Carlos Alberto dos Santos Treichel, Maria Giovana Borges Saidel, Ana Laura Salomé Lourencetti, Lívia Penteado Pinheiro, Sulamita Gonzaga Silva Amorim, Rosana Teresa Onocko Campos   +5 more
openaire   +1 more source

Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening

Advanced Science, EarlyView.
Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun, He Li, Xu Zhu, Zijian Zhang, Deshan Ren, Shuai Ding, Yan Li   +6 more
wiley   +1 more source

Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils

Advanced Science, EarlyView.
We show that immune cells (neutrophils) synthesize, uptake, and store catecholamine neurotransmitters such as dopamine or adrenaline. They also release them in response to specific stimuli (serotonin), which we directly visualize using fluorescent nanosensors. We further demonstrate that catecholamines affect neutrophil functions (NETosis) and platelet
Jennifer Mohr, Anne Schmitz, Meshkat Dinarvand, Franziska Wulfert, Sangeetha Shankar, Bjoern F. Hill, Michael Wojak, Juliana Gretz, Marie Britz, Elsa Neubert, Magdalena Shumanska, Sofia Kaushik, Linda Kartaschew, Ivan Bogeski, James Daniel, Sebastian Jung, Johannes Eble, Guido Wabnitz, Luise Erpenbeck, Sebastian Kruss   +19 more
wiley   +1 more source

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang, Baoshuai Liang, Liangmin Fu, Weiliang Deng, Yuyan Jiang, Weiping Xu, Jinwei Chen, Ya Zhou, Ke Wu, Jiaguo Huang   +9 more
wiley   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Evaluating enterprise resource planning (ERP) post implementation problems in Egypt: Findings from case studies of governmental, multinational and private Egyptian organisations

Enterprise Resource Planning (ERP) has been described as a business system supported by software that enables an organization to manage the efficient and effective use of an enterprise’s materials and resources by providing an integrated system for the ...
Hubbard, Nick J., El Sayed, May, Tipi, Nicoleta S.   +2 more
core  

Other title: Evaluating Delays in the System's Implementation

, 2015
application/pdf; "December 2015."; "A Report to the Legislative Post Audit Committee ...
Etzel, Matt.
core