Results 101 to 110 of about 2,969,586 (307)

The E3 ubiquitin ligase RHB1A and the transcription factor GRF1 form a regulatory module that orchestrates the trade-off between photosynthetic growth and salt tolerance in poplar

Plant Communications
Salt stress imposes a major constraint on plant growth and prompts plants to suppress growth-related processes, including photosynthesis, to prioritize stress defense and survival.
Kai Chen, Xiaoning Hao, Lulu Zhao, Ningning Chen, Li Xu, Heng Huang, Tiannan Luo, Wensen Shi, Jiale Zhao, Sijia Li, Yubo Wang, Yongran Luo, Yao Li, Shaoming Liang, Yuxuan Ren, Jianquan Liu, Tao Ma, Yuanzhong Jiang   +17 more
doaj   +1 more source

Magnetoreceptor Promotes Hepatocellular Carcinoma Development and Blunts Sorafenib‐Induced Ferroptosis by Regulating Iron Homeostasis

Advanced Science, EarlyView.
Magnetoreceptor (MagR) regulates iron homeostasis and mitochondrial function in hepatocellular carcinoma (HCC) cells. Specifically, MagR deficiency suppresses tumor cell proliferation, migration, and invasion and enhances sorafenib‐induced ferroptosis through iron accumulation.
Tao Wang, Chenghua Song, Xin He, Mengzhou Wang, Wuming Liu, Xiaolin Wang, Yuanyuan Zhang, Jia Zhang, Lin Zhang, Dan Li, Yu Zhang, Zheng Wu, Yi Lyu, Rongqian Wu   +13 more
wiley   +1 more source

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

Advanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu, Jingbo Dong, Qiufang Gong, Xuejiao Song, Zhifa Shen, Chao Liang   +5 more
wiley   +1 more source

Coriolopsis strumosa as an Orchid Endophytic Fungus and Its Spatial Distribution in Epidendrum sp. (Orchidaceae)

Microorganisms
Coriolopsis spp. are wood-decaying fungi that inhabit forests. They are mainly distributed in tropical and subtropical areas. Strain Epi910 was isolated from the asymbiotically germinated protocorm of Epidendrum sp. and identified as Coriolopsis strumosa.
Na Yao, Tao Wang, Jingwan Jiang, Yuqian Yang, Xiaolu Cao   +4 more
doaj   +1 more source

GIS and ex situ Plant Conservation

, 2012
Still, the rapid environmental changes including climate change, habitat loss and alteration, could pose some limitations on our ability to conserve target species effectively in situ (Sharrock & Jones, 2009). As a result, conservation biologists, policy makers and managers acknowledge the importance of ex situ conservation of target plants in botanic ...
Nikos Krigas, Kimon Papadimitriou, Antonios D.   +2 more
openaire   +2 more sources

CD112 Lactylation Drives Dual Immune Evasion From CD8+ T Cells and NK Cells

Advanced Science, EarlyView.
AARS2 functions as an intracellular lactate sensor and lactyltransferase, catalyzing CD112 K412 lactylation to block ubiquitination‐dependent degradation and stabilize CD112. This pathway suppresses CD8+ T‐cell and NK‐cell cytotoxicity, enabling dual immune evasion.
Zhuoshuo Xu, Xinyu Zhang, Fang Dong, Nenghao Shen, Jun Zhou, Zihan Xi, Zhenghao Wu   +6 more
wiley   +1 more source

Potato diversity at height: multiple dimensions of farmer-driven in-situ conservation in the Andes [PDF]

, 2009
In-situ conservation Two types of in-situ conservation of crop genetic resources can be distinguished: farmer-driven and externally driven. The first is subject of this thesis and refers to the persistence of potato genetic resources in areas where ...
de Haan, S., Haan, S., de
core  

In Situ and Ex Situ Conservation Measures

Abstract The effects of climate change and biodiversity loss are global and not limited by national borders, with forest ecosystems, in particular, suffering under increasing pressure. To preserve and maintain species genetic diversity, well-considered in situ and ex situ measures are needed.
Barbara Fussi, Muhidin Šeho, Darius Kavaliauskas   +2 more
openaire   +1 more source

MPP8 Facilitates DNA DSB Repair via NHEJ to Promote Chemoresistance of TNBC Independent of Methyl‐H3K9 Binding

Advanced Science, EarlyView.
Chemoresistance is often linked to elevated DNA repair. MPP8 is found to promote breast cancer chemoresistance as a novel NHEJ accessory factor independent of its epigenetic functions. Through multiple protein interactions, MPP8 facilitates association of DNAPK and ligase complexes to promote DNA repair progression.
Rupa Kumari, Jia Fang
wiley   +1 more source

Stepwise allelic trajectory of ETP2 underlies trade-off between UVB tolerance and submergence adaptation in Arabidopsis thaliana

Nature Communications
Strong UVB radiation critically restricts plant growth, yield, and distribution, while mechanisms enabling adaptation to intense UVB remain unclear. Here, we uncover that the F-box ubiquitin E3 ligase UVBT1 (also known as ETP2) is indispensable for UVB ...
Meng Liu, Kai Yang, WenJie Yang, Han Zhang, Wang Chen, Songyi Yang, Yan Song, Wensen Shi, Shangling Lou, Yu Han, Yingjun Yao, Jing Hou, Xuemeng Gao, Shaobo Gu, Jianquan Liu, Huanhuan Liu   +15 more
doaj   +1 more source