Results 81 to 90 of about 41,812 (301)

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

Advanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang, Di Cui, Fanzheng Meng, Xu Zhu, Liang Zhu, Liang Wu, Haifeng Hu, Jizhou Wang, Hanhui Yao, Lianxin Liu   +9 more
wiley   +1 more source

In-Situ & Ex-Situ Conservation Talk Session

, 2020
Dr Siti Khairiyah Mohd Hatta was invited as a speaker in "In-Situ & Ex-Situ Conservation Talk Session on 23 November 2020.
UiTM, Fakulti Sains Gunaan
core  

Gap analyses to support ex situ conservation of genetic diversity in Magnolia, a flagship group

, 2013
Worldwide about one third of all plant species is estimated to be threatened with extinction. Plants are generally under-represented in conservation. However, the global strategy for plant conservation (GSPC) sets forth 16 targets to halt the current and
Kramer, Andrea, Sharrock, Suzanne, Samain, Marie-Stéphanie, Cuesta Moliner, Candela, Cires Rodríguez, Eduardo, De Smet, Yannick, Rodriguez, Eduardo Cires, Gibbs, Douglas, Oldfield, Sara, Goetghebeur, Paul, Smet, Yannick De   +10 more
core   +1 more source

Global strategy for the conservation and use of Vigna

, 2023
This publication aims to provide a framework for the efficient and effective ex situ conservation of globally important collections of Vigna crops and their wild relatives.The development of this Global Crop Conservation Strategy was funded by the German
Takahashi, Yu, Olaniyi, Oyatomi, Nair, Ramakrishnan M., Scheldeman, Xavier, Vandelook, Filip, Giovannini, Peter, Pujar, Mahesh, Cockel, Christopher, Tallury, Shyam, van Zonneveld, Maarten   +9 more
core   +1 more source

A review of the advances and perspectives in sequencing technologies for analysing plant epigenetic responses to abiotic stress

Plant Stress
Abiotic stresses, such as drought, salinity, heat, and cold constrain plant growth and productivity by influence plant internal regulatory networks. Transcriptional/epigenetic regulation, which encompasses mechanisms such as DNA methylation, histone ...
Siqing Fan, Hua Yang, Yufang Hu, Ling Zhang, Mingkun Huang   +4 more
doaj   +1 more source

Beyond Percolation: Graphene‐Enabled Network Reinforcement Enhances Thermal Transport in Paraffin Phase‐Change Composites

Advanced Science, EarlyView.
Expanded‐graphite/graphene‐nanoplatelet hybrids deliver a near‐order‐of‐magnitude thermal‐conductivity enhancement in paraffin phase‐change materials. A microCT‐informed 3D modeling framework resolves the percolating EG backbone and captures sub‐voxel GNP enrichment, quantitatively linking microstructure to heat flow and revealing a graphene‐enabled ...
Thomas Hoke, Jackson Hoke, Shucheng Guo, Brittany Chan, Xi Chen   +4 more
wiley   +1 more source

Population variation in fatty acid composition and response to climatic factors in Malania oleifera Chun et S.K. Lee

BMC Plant Biology
Malania oleifera Chun et S.K. Lee is a woody oil tree species and is rich in nervonic acid, which is associated with brain development. The variation in fatty acid composition and its response to environmental factors in natural populations has not been ...
Hongguo Li, Ruizhen Wang, Zuwei Tian, Bingjiang Zhou, Runmei Duan, Ran He, Leiming Dong   +6 more
doaj   +1 more source

The E3 ubiquitin ligase RHB1A and the transcription factor GRF1 form a regulatory module that orchestrates the trade-off between photosynthetic growth and salt tolerance in poplar

Plant Communications
Salt stress imposes a major constraint on plant growth and prompts plants to suppress growth-related processes, including photosynthesis, to prioritize stress defense and survival.
Kai Chen, Xiaoning Hao, Lulu Zhao, Ningning Chen, Li Xu, Heng Huang, Tiannan Luo, Wensen Shi, Jiale Zhao, Sijia Li, Yubo Wang, Yongran Luo, Yao Li, Shaoming Liang, Yuxuan Ren, Jianquan Liu, Tao Ma, Yuanzhong Jiang   +17 more
doaj   +1 more source

An Integrated DNA Nanoprobe for Intranuclear Imaging and in Situ Profiling of OGG1 Activity

Advanced Science, EarlyView.
The TP‐SA nanoprobe, integrating an AS1411 aptamer for nuclear delivery and a FRET array for signal amplification, enables real‐time tracking of nuclear OGG1 activity. It reveals cell‐line‐specific basal OGG1 levels and shows clinical promise using pneumonia patients’ lavage fluid.
Mingzhu Zhao, Xuemei Sun, He Li, Bangming Wang, Mengting Pan, Zhen Ma, Rong‐Mei Kong, Weiheng Kong, Yan Zhao, Fengli Qu   +9 more
wiley   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source