Results 51 to 60 of about 17,179 (263)

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

Advanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li, Zhongya Zhai, Haiyi Yu, Renjie Qiu, Fengyu Li, Luxi Xiao, Boxi Huang, Huiying Liu, Jiayong He, Bowen Cai, Jiawen Chen, Jiang Yu, Guoxin Li, Tao Chen   +13 more
wiley   +1 more source

Causal Mediation Mechanism of Endogenous Hormones in Seedling Growth Response of Picea abies and Picea crassifolia to Post-Sunset Supplemental Light Durations

Applied Sciences
Post-sunset supplemental light promotes Picea seedling stem elongation, but the underlying hormonal regulation mechanisms on interspecific differences in spruce growth response to photoperiod remain unclear.
Jinping Zhang, Minghui Chen, Yin Cao, Zhihong Niu, Boyang Liu, Fangqun Ouyang, Junhui Wang, Mulualem Tigabu   +7 more
doaj   +1 more source

Conservation du lemur aux yeux turquoise (Eulemur flavifrons)

Revue de Primatologie, 2014
Depuis sa redécouverte en 1985 le lémur aux yeux turquoise a bénéficié de mesures de protection croissantes dans son aire de répartition et de programmes de reproduction en parc zoologique en Amérique du nord, en Europe ainsi qu’à Madagascar.
Brice Lefaux
doaj   +1 more source

CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity

Advanced Science, EarlyView.
Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung, Alexander Beer, Susmita Ghosh, Ekaterina Pylaeva, Belal Alshaar, Tobias Tertel, Nils Bastian Leimkühler, Thomas Schroeder, Janine Gronewold, Nina Hagemann, Ayan Mohamud Yusuf, Benedikt Frank, Yiqiao Zhang, Dennis Nagel, Kim Schloeßer, Laura Karsch, Emily Hedtfeld, Sabrina Lohmann, Kathrin Blank, Andreas Kraus, Max Krumbein, Nastassia Kabankova, Hongxiao Wang, Almke Bader, Mathis Richter, Fengjun Zhang, Raphael Chevre, Bernd Giebel, Stephan Lang, Anika Grüneboom, Daniela Maier‐Begandt, Anja Hasenberg, Oliver Soehnlein, Hans Christian Reinhardt, Sven Heiles, Jianxu Chen, Jadwiga Jablonska, Albert Sickmann, Dirk M. Hermann, Matthias Gunzer   +39 more
wiley   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

The prevalence of simian malaria in wild long-tailed macaques throughout Peninsular Malaysia

Scientific Reports
The parasite Plasmodium knowlesi has been the sole cause of malaria in Malaysia from 2018 to 2022. The persistence of this zoonotic species has hampered Malaysia’s progress towards achieving the malaria-free status awarded by the World Health ...
Shahhaziq Shahari, Mohd Lutfi Bin Abdullah, Anis Adlina Binti Isman Rohimly, Norsharina Binti Ashrat, Amirah Amir, Wahib Mohammed Mohsen Atroosh, Mun Yik Fong, Yee Ling Lau   +7 more
doaj   +1 more source

Plastid genome evolution and phylogenomics with broad taxon sampling: insights into intrafamilial classification of Hamamelidaceae

Frontiers in Plant Science
Hamamelidaceae, within the order Saxifragales, comprises 27 genera and approximately 120 species. The family has a pantropical and temperate distribution across the Americas, Asia, Africa, and Australia.
Sadaf Habib, Yong Shi, Jie Zhang, Wyckliffe Omondi Omollo, Dennis Stevenson, Jinlong Li, Yangjun Lai, Yangjun Lai, Chen Feng   +8 more
doaj   +1 more source

Unveiling prey preferences of endangered wild Malayan tiger, Panthera tigris jacksoni, in Peninsular Malaysia through scat analysis via COI DNA metabarcoding [PDF]

Nature Conservation
Understanding the prey preference of Malayan tiger (Panthera tigris jacksoni) in Malaysia is important to guide conservation planning initiatives. The utilisation of DNA metabarcoding provides valuable insights, particularly in the field of carnivora ...
Millawati Gani, Frankie Thomas Sitam, Zubaidah Kamarudin, Siti Suzana Selamat, Nik Mohd Zamani Awang, Hani Nabilia Muhd-Sahimi, Michael Wong, Baharim Selat, Nur Fatin Khairunnisa Abdullah-Halim, Lim Shu Yong, Ling Fong Yoke, Salmah Yaakop, Abd Rahman Mohd-Ridwan, Badrul Munir Md-Zain   +13 more
doaj   +3 more sources

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Global invasive alien plant management lists: Assessing current practices and adapting to new demands

Plant Diversity
Invasive alien species (IAS) significantly threaten global biodiversity and ecosystem stability. Despite increasing management efforts, a critical knowledge gap existed in understanding commonalities and disparities among national strategies. We analyzed
Fei-Fei Li, Qiang Hao, Xia Cui, Ruo-Zhu Lin, Bin-Sheng Luo, Jin-Shuang Ma   +5 more
doaj   +1 more source