Results 131 to 140 of about 4,133 (244)

EX VITRO ROOTING AND ACCLIMATIZATION OF Ilex paraguariensis A. St Hil. MICROCUTTINGS

open access: yes, 2016
The technique of microcutting and ex vitro rooting can result in plantlets with better quality of radicular system and larger number of secondary roots, when compared with conventional cutting. The objective of this work was to evaluate the ex vitro rooting and acclimatization of holly microcuttings in different doses of phytoregulator indole-3-butyric
Tronco, Kenia Michele de Quadros   +3 more
openaire   +1 more source

Navigating Human Astrocyte Differentiation: Direct and Rapid One‐Step Differentiation of Induced Pluripotent Stem Cells to Functional Astrocytes Supporting Neuronal Network Development

open access: yesGlia, Volume 74, Issue 9, September 2026.
One‐step protocol enabling direct differentiation of human iPSCs into functional astrocytes within 5 weeks. Validated in > 60 lines across 10 labs. iPSC‐astrocytes support robust neuronal network development in co‐culture. ABSTRACT Astrocytes play a pivotal role in neuronal network development.
Imke M. E. Schuurmans   +39 more
wiley   +1 more source

Intranasal Administration of Isoeugenol Improves Memory Deficits in APP/PS1 Old Mice—A Role Beyond Nrf2 Activation?

open access: yesThe FASEB Journal, Volume 40, Issue 15, 15 August 2026.
Inactivation of the Nrf2/Are pathway in AD leads to decreased antioxidant and anti‐inflammatory response and to the accumulation of beta‐amyloid (Aβ) plaques, resulting in cognitive failure. Treatment with Isoeugenol activates Nrf2, reversing these outcomes by promoting antioxidant response in neuronal cells (N2a) and by increasing the anti ...
Ana Silva   +14 more
wiley   +1 more source

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 29, 7 August 2026.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He   +9 more
wiley   +1 more source

Ambient Light‐Activatable Luminescent Particle‐Embedded Conformal Patch for Photochemical Tissue Bonding and Photobiomodulated Healing

open access: yesAdvanced Materials, Volume 38, Issue 44, 7 August 2026.
We report a wearable photonic patch integrating room light‐ and sunlight‐activatable luminescent particles (RSLPs) for both photochemical tissue bonding and photobiomodulation. RSLPs harvest ambient light and emit red luminescence to drive chlorin e6–mediated collagen crosslinking.
Kyungjoo Jo   +12 more
wiley   +1 more source

Molecular Docking‐Guided Engineering of TPGS/Tween 80 Mixed Micelles for the Intranasal Delivery of Paliperidone Palmitate

open access: yesAdvanced Therapeutics, Volume 9, Issue 8, August 2026.
A nanoscale drug delivery system is developed to improve how an antipsychotic reaches the brain. Using computer‐guided design, mixed micelles are engineered to enhance drug solubility and nasal transport. The system shows improved release and effectiveness in animal models, reducing symptoms while maintaining brain safety and structure.
Poorva Maske   +5 more
wiley   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

open access: yesAdvanced Science, Volume 13, Issue 45, 13 August 2026.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu   +18 more
wiley   +1 more source

Home - About - Disclaimer - Privacy