Results 91 to 100 of about 242,368 (323)
Swiss Medical Weekly, 2003 Acute exacerbations of COPD (AECOPD) are a common cause of morbidity and mortality. There is a need for a standardised definition of an exacerbation of COPD. The common aetiological factors are bacterial, viral infection and air pollutants. Exacerbations of COPD may adversely affect the natural history of COPD.
openaire +4 more sources
FEBS Open Bio, EarlyView.Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei +7 more
wiley +1 more source
International Journal of COPD, 2021 Jong Geol Jang, June Hong Ahn, Hyun Jung Jin Division of Pulmonology and Allergy, Department of Internal Medicine, College of Medicine, Yeungnam University and Regional Center for Respiratory Diseases, Yeungnam University Medical Center, Daegu, South ...
Jang JG, Ahn JH, Jin HJ
doaj
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
Aging and Cancer, EarlyView.This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal +8 more
wiley +1 more source
Aging and Cancer, EarlyView.Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley +1 more source
Impact of symptom variability on clinical outcomes in COPD: analysis of a longitudinal cohort
International Journal of COPD, 2019 Mi-Ae Kim,1 Min-Kang Suh,1 Jisoo Park,1 Jung-Hyun Kim,1 Tae-Hoon Kim,1 Eun Kyung Kim,1 Yeon-Mok Oh,2 Sang-Do Lee,2 Ji-Hyun Lee1 1Department of Pulmonology, Allergy and Critical Care Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Republic
Kim MA +8 more
doaj
The Unresolved Role of Interferon-λ in Asthma Bronchiale
Frontiers in Immunology, 2017 Asthma bronchiale is a disease of the airways with increasing incidence, that often begins during infancy. So far, therapeutic options are mainly symptomatic and thus there is an increasing need for better treatment and/or prevention strategies.
Nina Sopel +3 more
doaj +1 more source
Vaccine: XBackground: The link between individuals’ vaccine attitudes and their social networks has been widely studied, but less is known about how these networks impact broader health behaviors like precautionary measures during the COVID-19 pandemic.
Aditya S. Khanna +3 more
doaj
Media Environment, Dual Process and Polarization: A Computational Approach [PDF]
arXiv, 2019 News articles of varying degrees of truthfulness and political alignment, and their influences on the political opinions of the media consumers are modeled as a Bayesian network incorporating a mixture of ideas from dual-reasoning models of Motivated Reasoning and Analytic/Intuitive Reasoning.
arxiv
Carrier confinement and alloy disorder exacerbate Auger-Meitner recombination in AlGaN ultraviolet light-emitting diodes [PDF]
Appl. Phys. Lett. 125, 021109 (2024)The quantum efficiency of AlGaN ultraviolet light-emitting diodes (LEDs) declines (droops) at increasing operating powers due to Auger-Meitner recombination (AMR). Using first-principles density-functional theory, we show that indirect AMR mediated by electron-phonon coupling and alloy disorder can induce bulk $C$ coefficients as large as $\sim10^{-31}$
arxiv +1 more source