Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Efficacy and safety of mepolizumab in severe eosinophilic asthma: a systematic review and meta-analysis. [PDF]
Li Y, Li J, Yang H, Wu L.
europepmc +1 more source
3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram +5 more
wiley +1 more source
HO-1-Enriched Lung-Derived Exosomes Mediate Cognitive Impairment in a Mice Model of COPD Exacerbation. [PDF]
Yin GY +5 more
europepmc +1 more source
Bright Monocompound Metal Halide Scintillator for Fast Neutron Radiography
Metal halide scintillator, tetraphenylphosphonium manganese bromide (TPP2MnBr4), provides a significant benefit for fast neutron imaging. A fourfold increase in efficiency over traditional zinc sulfide screens is achieved by efficiently utilizing neutron interactions within its homogeneous structure.
Aditya Bhardwaj +13 more
wiley +1 more source
Leveraging Machine Learning and Real-World Data to Predict Chronic Obstructive Pulmonary Disease Exacerbations. [PDF]
Panettieri RA +6 more
europepmc +1 more source
Dynamically Adaptive Wrinkle‐Structured Light‐Regulating Films for Energy‐Efficient Buildings
A scalable, moisture‐responsive cellulose nanofibril/polyvinyl alcohol (CNF/PVA)‐glycerol film with switchable wrinkled surfaces for dynamic light regulation is developed. Compared to glass, it achieves tunable light diffusion for daylight harvesting, thermal regulation, and privacy control.
Jiaying Zhu +8 more
wiley +1 more source
Frequency and severity of COPD exacerbations and future risk of exacerbations and mortality: an observational cohort study in Canada. [PDF]
Duong ML +6 more
europepmc +1 more source
Antibiotics for COPD exacerbations [PDF]
Wassim W, Labaki, MeiLan K, Han
openaire +2 more sources

