Results 71 to 80 of about 119,332,414 (225)
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
On the exact sampling distribution of L-statistics [PDF]
This paper shows that linear functions of order statistics (L-statistics) based on random samples have a Fundamental Skew distribution (Arellano-Valle Genton, 2003).
Corrado Crocetta, Nicola Loperfido
core
Distribution of the product of a pair of independent two-sided power variates
, 2016 : The distributions of algebraic functions of random variables are important in theory of probability and statistics and other areas such as engineering, reliability, and actuarial applications, and many results based on various distributions are ...
Selim Gündüz +3 more
core +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Assessing the Magnitude of the Concentration Parameter in a Simultaneous Equations Model [PDF]
Poskitt and Skeels (2003) provide a new approximation to the sampling distribution of the IV estimator in a simultaneous equations model. This approximation is appropriate when the concentration parameter associated with the reduced form model is small ...
C. L. Skeels, D. S. Poskitt
core
Symbolic computing the exact distributions of L-statistics from a uniform distribution
Linear combination, order statistics, uniform distribution, exact distribution, symbolic differentiation,
T. Ramallingam
core +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
About the exact and asymptotic distribution of the Gini coefficient [PDF]
, 2010 In this paper we deal with the distribution of the Gini Concentration Index (G). We derive its exact sample distribution which is useful only for small sample sizes and basing on the classic results for L-statistics of Egorov and Nevronov we prove the ...
Martínez Camblor, Pablo +3 more
core +1 more source
Threonine 348 regulates the subcellular localization of PTEN
FEBS Open Bio, EarlyView.Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley +1 more source