Results 111 to 120 of about 1,376,473 (288)
Metric inequalities for polygons
Journal of Computational Geometry, 2013 Let A1,A2,…,An be the vertices of a polygon with unit perimeter, that is Σi |Ai Ai+1|=1. We derive various tight estimates on the minimum and maximum values of the sum of pairwise distances, and respectively sum of pairwise squared distances among its ...
Adrian Dumitrescu
doaj +1 more source
Exact inference in diagnosing value-at-risk estimates: A Monte Carlo device [PDF]
In this note a Monte Carlo approach is suggested to determine critical values for diagnostic tests of Value-at-Risk models that rely on binary random variables. Monte Carlo testing offers exact significance levels in finite samples.
Herwartz, Helmut
core
The exact distribution of exogenous variable coefficient estimators [PDF]
Journal of Econometrics, 1984 This paper derives the exact probability density function of the instrumental variable estimator of the exogenous variable coefficient vector in a structural equation containing \(n+1\) endogenous variables and N degrees of overidentification. The derivations make use of an operator calculus which simplifies the algebra of invariant polynomials with ...
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Bayesian inference on reliability parameter with non-identical-component strengths for Rayleigh distribution [PDF]
Journal of Mahani Mathematical ResearchIn this paper, we delve into Bayesian inference related to multi-component stress-strength parameters, focusing on non-identical component strengths within a two-parameter Rayleigh distribution under the progressive first failure censoring scheme.
Akram Kohansal
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Approximation of functions from generalized Nikol’skii– Besov classes by entire functions in Lebesgue spaces(in Ukrainian) [PDF]
Математичні Студії, 2013 Exact-order estimates for the approximations of functions ofclasses $S^{Omega}_{p,{heta}}B(mathbb{R}^d)$ by entirefunctions with the spectrum of a special form in the space$L_q(mathbb{R}^d)$ for some relations between the parameters$p$ and $q$, are ...
V. V. Myroniuk, S. Ya. Yanchenko
doaj
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source