Results 91 to 100 of about 323,983 (267)

Large Igneous Province thermogenic greenhouse gas flux could have initiated Paleocene-Eocene Thermal Maximum climate change

Nature Communications, 2019
The Paleocene-Eocene Thermal Maximum constitutes one of the largest climate perturbations in Earth’s history, but its exact causes are not well known.
Stephen M. Jones, Murray Hoggett, Sarah E. Greene, Tom Dunkley Jones   +3 more
doaj   +1 more source

Accounting estimates in financial statements and their disclosure by some South African construction companies

Journal of Economic and Financial Sciences, 2013
Accounting estimates form part of the preparation of financial statements and should not affect faithful representation. The use of accounting estimates does not yield exact amounts, but, rather, amounts based on assumptions.
Elsje Raubenheimer
doaj   +1 more source

The exact distribution of exogenous variable coefficient estimators [PDF]

Journal of Econometrics, 1984
This paper derives the exact probability density function of the instrumental variable estimator of the exogenous variable coefficient vector in a structural equation containing \(n+1\) endogenous variables and N degrees of overidentification. The derivations make use of an operator calculus which simplifies the algebra of invariant polynomials with ...
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Metric inequalities for polygons

Journal of Computational Geometry, 2013
Let A1,A2,…,An be the vertices of a polygon with unit perimeter, that is Σi |Ai Ai+1|=1. We derive various tight estimates on the minimum and maximum values of the sum of pairwise distances, and respectively sum of pairwise squared distances among its ...
Adrian Dumitrescu
doaj   +1 more source

Estimating exact form of generalisation errors

, 1999
A novel approach to estimate generalisation errors of the simple perceptron of the worst case is introduced. It is well known that the generalisation error of the simple perceptron is of the form d/t with an unknown constant d which depends only on the dimension of inputs, where t is the number of learned examples.
openaire   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Bayesian inference on reliability parameter with non-identical-component strengths for Rayleigh distribution [PDF]

Journal of Mahani Mathematical Research
In this paper, we delve into Bayesian inference related to multi-component stress-strength parameters, focusing on non-identical component strengths within a two-parameter Rayleigh distribution under the progressive first failure censoring scheme.
Akram Kohansal
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Exact estimates for monotone interpolation

Journal of Approximation Theory, 1980
AbstractLet 0 = xo < x1 < … < xn = 1, 0 = yo < y1 < … < yn \̌ 1 and let A, B, C be defined by (3); suppose further that C ⩾ con−1. We prove that for some constant c = c(co), depending only on co, there exists an algebraic polynomial P of degree ⩽ cn In (e + AB) for which P(xi) = yi, i = 1,…, n, and P′(x) ⩾ 0, 0 ⩽ x ⩽ 1.
openaire   +1 more source