Results 81 to 90 of about 323,983 (267)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Approximation by complex Bernstein-Kantorovich and Stancu-Kantorovich polynomials and their iterates in compact disks

Journal of Numerical Analysis and Approximation Theory, 2008
In this paper, Voronovskaja-type results with quantitative upper estimates and the exact orders in simultaneous approximation by some complex Kantorovich-type polynomials and their iterates in compact disks in \(\mathbb{C}\) are obtained.
Sorin G. Gal
doaj   +2 more sources

Estimates for the difference between approximate and exact solutions to stochastic differential equations in the G-framework

Journal of Taibah University for Science, 2019
This article investigates the Euler-Maruyama approximation procedure for stochastic differential equations in the framework of G-Browinian motion with non-linear growth and non-Lipschitz conditions.
Faiz Faizullah, Ilyas Khan, Mukhtar M. Salah, Ziyad Ali Alhussain   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Internal exact controllability of the linear population dynamics with diffusion

Electronic Journal of Differential Equations, 2004
We consider the internal exact controllability of a linear age and space structured population model with nonlocal birth process. The control acts only in a spatial subdomain and only for small age classes.
Bedr'Eddine Ainseba, Sebastian Anita
doaj  

Exact Formulation for Stochastic ML Estimation of DOA

IEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences, 2010
This paper addresses the issue of Unconditional or Stochastic Maximum likelihood (SML) estimation of directions-of-arrival (DOA) finding using sensors with arbitrary array configuration. The conventional SML estimation is formulated without an important condition that the covariance matrix of signal components must be non-negative definite.
CHEN, Haihua, SUZUKI, Masakiyo
openaire   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

Null controllability of a nonlinear heat equation

Abstract and Applied Analysis, 2002
We study the internal exact null controllability of a nonlinear heat equation with homogeneous Dirichlet boundary condition. The method used combines the Kakutani fixed-point theorem and the Carleman estimates for the backward adjoint linearized system ...
G. Aniculăesei, S. Aniţa
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source