Results 61 to 70 of about 323,983 (267)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi +6 more
wiley +1 more source
Journal of Inequalities and Applications, 2017 In this paper, a semidiscrete finite element method for solving bilinear parabolic optimal control problems is considered. Firstly, we present a finite element approximation of the model problem.
Yuelong Tang, Yuchun Hua
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Researches in MathematicsExact in order estimates are obtained for the best $m$-term trigonometric approximations of the classes of periodic multivariate functions of mixed smoothness (Nikol'skii-Besov $B^{\boldsymbol{r}}_{p, \theta}$ and Sobolev $W^{\boldsymbol{r}}_{p ...
K.V. Pozharska, A.S. Romanyuk
doaj +1 more source
Exact Nonlinear State Estimation
Journal of the Atmospheric SciencesAbstract The majority of data assimilation (DA) methods in the geosciences are based on Gaussian assumptions. While such approximations facilitate efficient algorithms, they cause analysis biases and subsequent forecast degradations. Nonparametric, particle-based DA algorithms have superior accuracy, but their application to high-dimensional models ...
openaire +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Exact and empirical estimation of misclassification probability
CoRR, 2014 We discuss the problem of risk estimation in the classification problem, with specific focus on finding distributions that maximize the confidence intervals of risk estimation. We derived simple analytic approximations for the maximum bias of empirical risk for histogram classifier.
openaire +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source