Results 111 to 120 of about 2,188,866 (304)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Estimates for the deviation from exact solutions of variational problems with power growth functionals [PDF]
, 2005 We study the nonlinear power growth variational problem J_{\alpha}[w]:=\int_{\Omega}\left[\frac{1}{\alpha}\left|\nabla w\right|^{\alpha}-fw\right]dx\rightarrow\textrm{min} and establish directly ...
Repin, Sergey, Bildhauer, Michael
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Null controllability of a nonlinear heat equation
Abstract and Applied Analysis, 2002 We study the internal exact null controllability of a nonlinear heat equation with homogeneous Dirichlet boundary condition. The method used combines the Kakutani fixed-point theorem and the Carleman estimates for the backward adjoint linearized system ...
G. Aniculăesei, S. Aniţa
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
, 2016 We analyze a general class of difference operators H-epsilon = T-epsilon + V-epsilon on l(2)(((epsilon)Z)(d)), where V-epsilon is a multi-well potential and epsilon is a small parameter.
Klein, Markus, Rosenberger, Elke
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Nature Communications, 2019 The Paleocene-Eocene Thermal Maximum constitutes one of the largest climate perturbations in Earth’s history, but its exact causes are not well known.
Stephen M. Jones +3 more
doaj +1 more source
Chained, exact and superlative hedonic price changes: estimates from microdata
Scanner data are used to calculate chained, exact (and superlative) hedonic price indexes for television sets. The data source is available for a wide range of goods, the application providing an example of how this method can be more widely applied. The
Mick Silver, Christos Ioannidis
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source