Results 131 to 140 of about 547,457 (313)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Exact analytical Taub-NUT like solution in f(T) gravity

European Physical Journal C: Particles and Fields
We construct exact analytical Taub-NUT solutions in the context of f(T) gravity. We study the physical properties of the solutions, and compare them with those of the Taub-NUT solution in Einstein gravity.
Joshua G. Fenwick, Masoud Ghezelbash
doaj   +1 more source

A Variety of Novel Exact Solutions for Different Models With the Conformable Derivative in Shallow Water [PDF]

, 2020
Dipankar Kumar, Melike Kaplan, Md. Rabiul Haque, M.S. Osman, Dumitru Băleanu   +4 more
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Homotopy analysis method for solving KdV equations [PDF]

Surveys in Mathematics and its Applications, 2010
A scheme is developed for the numerical study of the Korteweg-de Vries (KdV) and the Korteweg-de Vries Burgers (KdVB) equations with initial conditions by a homotopy approach.
Hossein Jafari, M. A. Firoozjaee
doaj  

Exact and Numerical Solution of the Fractional Sturm–Liouville Problem with Neumann Boundary Conditions [PDF]

, 2022
Małgorzata Klimek, Mariusz Ciesielski, Tomasz Błaszczyk   +2 more
openalex   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Accurate Approximations for a Nonlinear SIR System via an Efficient Analytical Approach: Comparative Analysis

Axioms
The homotopy perturbation method (HPM) is one of the recent fundamental methods for solving differential equations. However, checking the accuracy of this method has been ignored by some authors in the literature.
Mona Aljoufi
doaj   +1 more source

EXACT SOLUTION OF SOME FRACTIONAL SYSTEMS OF PARTIAL DIFFERENTIAL EQUATIONS VIA THE SBA METHOD

, 2023
Bamogo Hamadou, Yaya Moussa, Francis Bassono, Youssouf Paré   +3 more
openalex   +1 more source