Results 131 to 140 of about 2,430,570 (319)

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Exact Solution of Unsteady Tank Drainage for Ellis Fluid

Journal of Applied Fluid Mechanics, 2018
In this work, we investigate the the problem of an unsteady tank drainage while considering an isothermal and incompressible Ellis fluid. Exact solution is gotten for a resulting non-linear PDE (partial differential equation)-subject to proper boundary ...
K. N. Memon, S. F. Shah, A A. M. Siddiqui   +2 more
doaj  

Exact Axially Symmetric Solution in f(T) Gravity Theory

Advances in High Energy Physics, 2014
A general tetrad field with sixteen unknown functions is applied to the field equations of f(T) gravity theory. An analytic vacuum solution is derived with two constants of integration and an angle Φ that depends on the angle coordinate ϕ and radial ...
Gamal G. L. Nashed
doaj   +1 more source

Stellar Dynamics: Exact Solution of the Self-Gravitation Equation [PDF]

, 1961
D. Lynden–Bell
openalex   +1 more source

An exact solution approach to warm inflation using Tsallis and Barrow holographic dark energy entropy within Rastall gravity. [PDF]

Eur Phys J Plus, 2022
Saleem R, Shahid I, Sabir M.
europepmc   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Exact Solutions of Linear Equations with Rational Coefficients by Congruence Techniques [PDF]

, 1966
I. Borosh, A. S. Fraenkel
openalex   +1 more source

A semi exact solution for a metallic phase in a Holstein-Hubbard chain at half filling with Gaussian anharmonic phonons. [PDF]

Sci Rep, 2021
Debnath D, Malik MZ, Chatterjee A.
europepmc   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Exact Solution for Water Evaporation During CO2 Injection

Water Resources Research
The objective of this study is to develop an analytical model for 1D gas‐water flow with evaporation of water into the mobile gas phase. The evaporation rate is proportional to the fluid‐fluid interfacial area, which is a function of the water saturation.
T. Russell, P. Bedrikovetsky
doaj   +1 more source